Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567164 | 0.85 | ENPP2 (0.40) | KDM4EENPP2 | |
| SCHEMBL9419742 | 0.81 | MAPT (0.37) | MAPTMEN1KMT2AHSP90AB1MPO | |
| SCHEMBL8993309 | 0.77 | MAPT (0.41) | MAPTMEN1KMT2AHSP90AB1CYP2A6 | |
| SCHEMBL28307656 | 0.75 | CYP2A6 (0.49) | MAPTMEN1KMT2ACYP2A6ALDH1A1 | |
| SCHEMBL10548363 | 0.75 | ENPP2 (0.46) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL38192 | 0.74 | IDO1 (0.46) | MAPTMEN1KMT2ACYP2A6ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28306691 | 0.74 | CYP2A6 (0.47) | MAPTMEN1KMT2ACYP2A6ALDH1A1 | |
| SCHEMBL7999091 | 0.73 | ENPP2 (0.41) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9364439 | 0.73 | SLC6A4 (0.41) | MAPTMEN1KMT2ACYP2A6ALDH1A1 | |
| Methane SCHEMBL4574569 | 0.72 | IDO1 (0.44) | MAPTMEN1KMT2ACYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005218-A | Antiparasitic salicylanilide derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-01-25 | — | — | US | disclosed |