Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9481830 | 0.81 | ALDH1A1 (0.49) | RAB9AMAPTALDH1A1TDP1SCN2A | |
| SCHEMBL11243947 | 0.79 | HTT (0.45) | HTR2ARAB9AMAPTALDH1A1TDP1 | |
| SCHEMBL10545920 | 0.78 | RAB9A (0.46) | RAB9AMAPTALDH1A1TDP1SCN2A | |
| SCHEMBL659165 | 0.74 | KMT2A (0.63) | RAB9AMAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL6153637 | 0.73 | RAB9A (0.52) | HTR2ARAB9AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL14598270 | 0.73 | ALDH1A1 (0.51) | RAB9AMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL6404075 | 0.71 | PTPRC (0.41) | MAPTALDH1A1KDM4E | |
| SCHEMBL6141237 | 0.70 | ALDH1A1 (0.56) | HTR2ARAB9AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8247254 | 0.70 | HTR2A (0.60) | HTR2ARAB9AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL6155113 | 0.70 | HTR2A (0.49) | HTR2ARAB9AMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053816-B1 | 1-SULFO-2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1988-05-04 | — | — | EP | disclosed |
| EP-0053816-A1 | 1-Sulfo-2-oxoazetidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |