Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9481830 | 0.81 | ALDH1A1 (0.49) | HTTALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL659165 | 0.80 | KMT2A (0.63) | HTTALDH1A1RAB9APOLBMAPT | |
| SCHEMBL10637787 | 0.79 | HTR2A (0.44) | ALDH1A1HTR2ARAB9AMAPTTDP1 | |
| SCHEMBL15152327 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1POLBSMN1; SMN2MAPTMEN1 | |
| SCHEMBL10545920 | 0.76 | RAB9A (0.46) | ALDH1A1RAB9APOLBSMN1; SMN2MAPT | |
| SCHEMBL29365592 | 0.75 | ALDH1A1 (0.47) | HTTALDH1A1HTR2ARAB9APOLB | |
| SCHEMBL8247254 | 0.73 | HTR2A (0.60) | HTTALDH1A1HTR2ARAB9APOLB | |
| SCHEMBL29171050 | 0.72 | HTR2A (0.59) | HTTALDH1A1HTR2ARAB9APOLB | |
| SCHEMBL11098324 | 0.71 | HTR2A (0.58) | HTTALDH1A1HTR2ARAB9APOLB | |
| SCHEMBL14598270 | 0.71 | ALDH1A1 (0.51) | HTTALDH1A1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053816-A1 | 1-Sulfo-2-oxoazetidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |