Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724018 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL5724109 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL12912355 | 0.87 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL6401181 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL10639422 | 0.86 | TPSAB1 (0.50) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL13712608 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL8587397 | 0.85 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL9519331 | 0.85 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL13713047 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL10633380 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742052-A | Antibacterial β-lactam compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0070204-B1 | CARBOXYLIC BETA-LACTAM COMPOUNDS AND THE PREPARATION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-19 | — | — | EP | disclosed |
| EP-0070204-A2 | Carboxylic beta-lactam compounds and the preparation thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1983-01-19 | — | — | EP | disclosed |