Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400164 | 0.93 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL9854866 | 0.93 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL562016 | 0.93 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL23199288 | 0.89 | CYP1A2 (0.50) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL28556696 | 0.88 | CYP1A2 (0.52) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL5724018 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL10636257 | 0.88 | TPSAB1 (0.49) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL5724109 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL10639271 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL12912355 | 0.87 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-6051569-A | 1'S, 5R, 6R-carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0826687-A1 | Carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0774465-A1 | Penem derivatives and antimicrobial agents containing the same | SUNTORY LIMITED (JP) | 1997-05-21 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-RE34960-E | Carbapenem compounds, and compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0161541-B1 | 6-[1-Hydroxyethyl]-2-SR8-1-methyl-1-carba-dethiapen-2-em-3-carboxylic acids | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4742052-A | Antibacterial β-lactam compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0070204-B1 | CARBOXYLIC BETA-LACTAM COMPOUNDS AND THE PREPARATION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-19 | — | — | EP | disclosed |
| US-4696923-A | THIENAMYCIN ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0165384-A1 | Carbapenem derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1985-12-27 | — | — | EP | disclosed |
| EP-0160876-A1 | 1-Hetero-6-/1-Hydroxyethyl/-2-SR8-1-carbadethiapen-2-EM-3-carboxylic acids | MERCK & CO. INC. (US) | 1985-11-13 | — | — | EP | disclosed |
| US-4552873-A | BACTERICIDES | SANKYO COMPANY LIMITED (JP) | 1985-11-12 | — | — | US | disclosed |
| EP-0072710-A1 | Carbapenem derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1983-02-23 | — | — | EP | disclosed |
| EP-0070204-A2 | Carboxylic beta-lactam compounds and the preparation thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1983-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | SMN1; SMN2 3757/4885ALDH1A1 1862/4885LMNA 3637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.