Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166445 | 0.84 | GAA (0.56) | SLC2A1LMNAMAPTHTTNPSR1 | |
| SCHEMBL1371186 | 0.81 | KDM4E (0.54) | MAPTGRM2IDO1GAAPOLB | |
| SCHEMBL10644152 | 0.80 | L3MBTL1 (0.50) | RAB9AGRM2IDO1CYP11B1CYP11B2 | |
| SCHEMBL10643826 | 0.74 | CA5A (0.40) | MAPTPKMGAAPOLB | |
| SCHEMBL1491118 | 0.73 | KDM4E (0.68) | SLC2A1LMNAMAPTRAB9AMITF | |
| SCHEMBL16832376 | 0.72 | SLC2A1 (1.00) | SLC2A1MAPTHTTDHFRGAA | |
| SCHEMBL10639487 | 0.69 | MEN1 (0.59) | LMNAMAPTRAB9ANPSR1GAA | |
| SCHEMBL18320779 | 0.69 | SLC2A1 (0.58) | SLC2A1LMNAMAPTDHFRMET | |
| SCHEMBL17458897 | 0.69 | SLC2A1 (0.58) | SLC2A1LMNAMAPTRAB9AMITF | |
| SCHEMBL17731477 | 0.68 | SLC2A1 (0.53) | SLC2A1LMNAMAPTRAB9AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288431-A1 | 3H-1,2,3-triazolo[4,5-d]pyrimidines | CIBA-GEIGY AG (CH) | 1988-10-26 | — | — | EP | disclosed |