Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643153 | 0.80 | SLC2A1 (0.57) | GRM2CYP11B1CYP11B2RAB9AIDO1 | |
| SCHEMBL1371186 | 0.80 | KDM4E (0.54) | GRM2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1460580 | 0.76 | ALDH1A1 (0.58) | L3MBTL1GRM2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL16832960 | 0.76 | SLC2A1 (0.68) | L3MBTL1GRM2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL10643826 | 0.76 | CA5A (0.40) | L3MBTL1ALDH1A1TAAR1KMT2A | |
| SCHEMBL18321167 | 0.73 | GRM2 (0.52) | L3MBTL1GRM2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL17459009 | 0.73 | L3MBTL1 (0.48) | L3MBTL1GRM2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL17731466 | 0.72 | L3MBTL1 (0.54) | L3MBTL1GRM2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL1460583 | 0.72 | CYP11B1 (0.51) | L3MBTL1CYP11B1CYP11B2ALDH1A1SMN1; SMN2 | |
| SCHEMBL16166445 | 0.71 | GAA (0.56) | L3MBTL1GRM2CYP11B1CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288431-A1 | 3H-1,2,3-triazolo[4,5-d]pyrimidines | CIBA-GEIGY AG (CH) | 1988-10-26 | — | — | EP | disclosed |