Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979306 | 0.84 | KMT2A (0.59) | CA12CA1CA2CA9KMT2A | |
| Water SCHEMBL10648619 | 0.81 | MEN1 (0.46) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL10644355 | 0.80 | MEN1 (0.51) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL10648543 | 0.79 | CA12 (0.42) | CA12CA1CA2CA9KMT2A | |
| Mitozolomide SCHEMBL97695 | 0.78 | MEN1 (0.64) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL10645833 | 0.76 | LMNA (0.39) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL3336299 | 0.75 | MEN1 (0.47) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL10648478 | 0.73 | MEN1 (0.44) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL31451982 | 0.71 | MEN1 (0.47) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL31452053 | 0.70 | CA12 (0.43) | CA12CA1CA2CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260291-A | Tetrazine derivatives | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1993-11-09 | — | — | US | claimed |
| US-20090170880-A1 | Methods and Means for the Treatment of Cancer | VAN TELLINGEN OLAF | 2009-07-02 | — | — | US | disclosed |
| US-5260291-A | Tetrazine derivatives | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1993-11-09 | — | — | US | disclosed |
| EP-0252682-A2 | Tetrazines | MAY & BAKER LIMITED (GB) | 1988-01-13 | — | — | EP | disclosed |