Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644450 | 0.89 | MCHR1 (0.54) | MCHR1METLTA4HMAPK14NPC1 | |
| SCHEMBL31033074 | 0.78 | LTA4H (0.44) | MCHR1LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL10644141 | 0.78 | CYP1A2 (0.53) | MCHR1LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL10644419 | 0.76 | MCHR1 (0.54) | MCHR1LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL10649038 | 0.76 | MCHR1 (0.54) | MCHR1LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL8326730 | 0.76 | MCHR1 (0.54) | MCHR1LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL7222828 | 0.76 | CYP1A2 (0.59) | MCHR1LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL1921437 | 0.76 | MET (0.52) | MCHR1METLTA4HMAPK14NPC1 | |
| SCHEMBL19150026 | 0.75 | ALDH1A1 (0.36) | TLR8NOS3NOS1NOS2SLC6A2 | |
| SCHEMBL30541526 | 0.74 | ADA (0.40) | ADATLR8NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390917-A | MRGX2 antagonists | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-07-04 | — | — | CN | disclosed |