Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | VDR | P11473 | 6/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11959661 | 0.81 | L3MBTL1 (0.49) | KDM4EVDRCYP2C9 | |
| SCHEMBL10649823 | 0.80 | CYP2C19 (0.40) | KDM4E | |
| SCHEMBL10645631 | 0.80 | PDE4B (0.40) | KDM4EPDE4BCYP2C9 | |
| SCHEMBL2625771 | 0.78 | SSTR4 (0.49) | KDM4ECYP2C9 | |
| SCHEMBL12207807 | 0.76 | FFAR4 (0.39) | KDM4EVDRAAK1HDAC3HDAC6 | |
| SCHEMBL7015786 | 0.76 | ALDH1A1 (0.44) | KDM4EESR1 | |
| SCHEMBL11951589 | 0.75 | ACHE (0.43) | KDM4EVDRAAK1 | |
| SCHEMBL13672486 | 0.74 | KDM4E (0.40) | KDM4EVDRESR1 | |
| SCHEMBL13990704 | 0.74 | KDM4E (0.42) | KDM4ERECQLESR1 | |
| SCHEMBL6060644 | 0.73 | SLC6A4 (0.35) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273242-A2 | 2-Pyri(mi)dylthio-aryl ether | BAYER AG (DE) | 1988-07-06 | — | — | EP | disclosed |