Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10543412 | 0.84 | LMNA (0.43) | LMNAPKMKMT2APOLBALDH1A1 | |
| SCHEMBL9531501 | 0.84 | LMNA (0.43) | LMNAPKMKMT2APOLBALDH1A1 | |
| SCHEMBL9531495 | 0.84 | LMNA (0.43) | LMNAPKMKMT2APOLBALDH1A1 | |
| SCHEMBL9529808 | 0.84 | LMNA (0.43) | LMNAPKMKMT2APOLBALDH1A1 | |
| SCHEMBL10538984 | 0.84 | LMNA (0.43) | LMNAPKMKMT2APOLBALDH1A1 | |
| SCHEMBL9530832 | 0.70 | ABCC9 (0.43) | LMNAPKMKMT2AALDH1A1MEN1 | |
| SCHEMBL9531246 | 0.70 | ABCC9 (0.43) | LMNAPKMKMT2AALDH1A1MEN1 | |
| SCHEMBL9530830 | 0.70 | ABCC9 (0.43) | LMNAPKMKMT2AALDH1A1MEN1 | |
| SCHEMBL9159171 | 0.69 | PGR (0.40) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL9530480 | 0.68 | ABCC9 (0.64) | LMNAALDH1A1LRRK2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150202-B1 | DI/TETRA-HYDROQUINOLINES | BEECHAM GROUP PLC (GB) | 1988-07-06 | — | — | EP | claimed |