Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TFPI | P10646 | 1/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.39 |
| ▸ | CALCR | P30988 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360974 | 0.93 | OPRM1 (0.46) | FOLH1TASP1KEAP1OPRM1OPRD1 | |
| SCHEMBL29772029 | 0.93 | OPRM1 (0.46) | FOLH1TASP1KEAP1OPRM1OPRD1 | |
| SCHEMBL29597397 | 0.91 | OPRM1 (0.42) | TASP1KEAP1NOD1OPRM1OPRD1 | |
| SCHEMBL29772026 | 0.91 | FOLH1 (0.45) | FOLH1TASP1KEAP1NOD1OPRM1 | |
| SCHEMBL29771993 | 0.91 | FOLH1 (0.45) | FOLH1NOD1OPRM1OPRD1OPRK1 | |
| SCHEMBL30920966 | 0.89 | NOD1 (0.52) | FOLH1NOD1 | |
| SCHEMBL29493327 | 0.89 | OPRM1 (0.45) | TASP1KEAP1OPRM1OPRD1OPRK1 | |
| SCHEMBL29771973 | 0.89 | FOLH1 (0.44) | FOLH1TASP1KEAP1OPRM1OPRD1 | |
| SCHEMBL29485672 | 0.88 | FOLH1 (0.48) | FOLH1TASP1KEAP1OPRM1OPRD1 | |
| SCHEMBL29485668 | 0.88 | FOLH1 (0.48) | FOLH1TASP1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113968911-B | insulin-Fc fusion protein and application thereof | 江苏晟斯生物制药有限公司 | 2023-10-10 | — | — | CN | disclosed |
| US-20230272030-A1 | INSULIN-FC FUSION PROTEIN AND APPLICATION THEREOF | JIANGSU GENSCIENCES INC. (CN) | 2023-08-31 | — | — | US | disclosed |
| CN-113968911-A | insulin-Fc fusion protein and application thereof | 江苏晟斯生物制药有限公司 | 2022-01-25 | — | — | CN | disclosed |