Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645458 | 0.81 | HDAC3 (0.43) | ALDH1A1MAPK1KMT2AHDAC6HDAC3 | |
| SCHEMBL10644960 | 0.75 | ABL1 (0.50) | ALDH1A1MAPK1KMT2AHDAC6HDAC3 | |
| SCHEMBL27451126 | 0.74 | MGLL (0.57) | ALDH1A1KMT2AL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL27453517 | 0.73 | LMNA (0.48) | ALDH1A1KMT2ALMNAL3MBTL1RAB9A | |
| SCHEMBL10645037 | 0.71 | GAA (0.51) | ALDH1A1KMT2ALMNAL3MBTL1TSHR | |
| SCHEMBL31227621 | 0.71 | KMT2A (0.60) | BCHEALDH1A1MAPK1KMT2AHDAC6 | |
| SCHEMBL31124620 | 0.70 | ITGB1 (0.42) | MAPK1KMT2ALMNAL3MBTL1 | |
| SCHEMBL31124633 | 0.70 | ITGB1 (0.42) | MAPK1KMT2ALMNAL3MBTL1 | |
| SCHEMBL10640864 | 0.70 | FFAR4 (0.42) | LMNARAB9ASMN1; SMN2GPR142 | |
| SCHEMBL10650169 | 0.69 | ITGB1 (0.41) | MAPK1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095278-B1 | 5-OXO-2-PYRROLIDINEPROPANOIC ACID DERIVATIVES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-11-30 | — | — | EP | disclosed |
| US-4617310-A | 5-oxo-2-pyrrolidinepropanoic acid derivatives and use as cognition activators | WARNER-LAMBERT COMPANY (US) | 1986-10-14 | — | — | US | disclosed |
| US-4559358-A | TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0095278-A2 | 5-Oxo-2-pyrrolidinepropanoic acid derivatives and their production | WARNER-LAMBERT COMPANY (US) | 1983-11-30 | — | — | EP | disclosed |