Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451126 | 0.87 | MGLL (0.57) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL27453115 | 0.76 | LMNA (0.56) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL27451710 | 0.76 | MAPT (0.52) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL27453518 | 0.75 | RAB9A (0.43) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL27453607 | 0.74 | KMT2A (0.44) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL27453610 | 0.74 | KMT2A (0.44) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL10647117 | 0.73 | BCHE (0.49) | LMNAKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL27452429 | 0.73 | LMNA (0.59) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL27452211 | 0.70 | HTT (0.64) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL27452291 | 0.69 | LMNA (0.60) | LMNAMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |