Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740818 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL9250005 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPT | |
| SCHEMBL9250009 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPT | |
| SCHEMBL9853982 | 0.81 | KDM4E (0.45) | ALDH1A1KDM4E | |
| SCHEMBL27314597 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPT | |
| SCHEMBL9853999 | 0.80 | POLB (0.58) | ALDH1A1KDM4EHSD17B10 | |
| Acetic Acid SCHEMBL9854087 | 0.79 | POLB (0.57) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9647783 | 0.78 | PTAFR (0.56) | — | |
| SCHEMBL9268772 | 0.78 | — | — | |
| SCHEMBL10647450 | 0.77 | PTAFR (0.64) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1029382-A | — | — | None | — | — | JP | disclosed |
| US-4906757-A | Process for the preparation of dextrorotatory 3-(3-pyridyl)-1H,3H-pyrrolo [1,2-c]-7-thiazolecarboxylic acid | RHONE-POULENC SANTE (FR) | 1990-03-06 | — | — | US | disclosed |
| US-4786645-A | ANTIALLERGENS, ANTIINFLAMMATORY | RHONE-POULENC SANTE (FR) | 1988-11-22 | — | — | US | disclosed |
| US-4783472-A | 1H,3H-pyrrol[1,2-c]thiazole derivatives and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1988-11-08 | — | — | US | disclosed |