SCHEMBL10648409

SCHEMBL10648409

C#CC(C)(CCCc1ccc(F)c(Oc2ccccc2)c1)c1ccc(OCC)c(OCC)c1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 1/20 0.34
CALM1 P0DP23 2/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
ATM Q13315 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
NTRK1 P04629 1/20 0.32
NTRK3 Q16288 1/20 0.32
NTRK2 Q16620 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10649075 0.92 FFAR1 (0.35) L3MBTL1SMN1; SMN2ATM
SCHEMBL7903533 0.90 LTA4H (0.39) L3MBTL1LMNAATM
SCHEMBL10649304 0.90 L3MBTL1 (0.36) L3MBTL1
SCHEMBL10651331 0.88 TTR (0.33)
SCHEMBL10739731 0.87 L3MBTL1 (0.37) L3MBTL1SMN1; SMN2LMNACALM1MEN1
SCHEMBL10651741 0.87 KIF11 (0.35) NPSR1
SCHEMBL10650335 0.86 FDFT1 (0.38) SMN1; SMN2NPSR1ALDH1A1
SCHEMBL10655295 0.86 S1PR1 (0.38)
SCHEMBL10649524 0.86 S1PR1 (0.34)
SCHEMBL10649059 0.86 TTR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0193189-B1 NOVEL COMPOUND, ITS PRODUCTION AND INSECTICIDAL AND ACARICIDAL COMPOSITION CONTAINING IT AS AN ACTIVE INGREDIENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-28 EP disclosed
US-4772633-A 6-pyridyl- and 6-phenyl-3-phenyl-1-hexenes and -1-hexynes, composition containing them, and insecticidal and acaricidal method of using them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-20 US disclosed
EP-0193189-A1 Novel compound, its production and insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-09-03 EP disclosed