Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4715345 | 0.94 | PTGS2 (0.53) | PTGS2ERN1MMP1MMP2MMP3 | |
| SCHEMBL9720714 | 0.94 | MAOB (0.49) | PTGS2PTGS1MAOBENPP2AKR1C3 | |
| SCHEMBL607349 | 0.88 | ENPP2 (0.52) | PTGS2MAOBENPP2AKR1C3 | |
| SCHEMBL9720723 | 0.85 | MAOB (0.55) | PTGS2PTGS1MAOBENPP2AKR1C3 | |
| SCHEMBL9720721 | 0.85 | MAOB (0.55) | PTGS2PTGS1MAOBENPP2AKR1C3 | |
| Benzaldehyde SCHEMBL28192263 | 0.80 | ALDH1A1 (0.58) | PTGS2AKR1C3 | |
| SCHEMBL10300269 | 0.78 | PTGS2 (0.62) | PTGS2PTGS1ENPP2CA12CA2 | |
| SCHEMBL7677302 | 0.78 | PTGS2 (0.62) | PTGS2PTGS1ENPP2CA12CA2 | |
| SCHEMBL27722400 | 0.78 | PTGS2 (0.59) | PTGS2AKR1C3 | |
| SCHEMBL3923767 | 0.77 | ALDH1A1 (0.50) | PTGS2ENPP2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136259-B1 | 4-HETEROCYCLYL-VINYL-4'-STYRYL-BIPHENYLS | CIBA-GEIGY AG (CH) | 1988-06-15 | — | — | EP | disclosed |
| US-4666627-A | FLUORESCENT BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1987-05-19 | — | — | US | disclosed |
| EP-0136259-A1 | 4-Heterocyclyl-vinyl-4'-styryl-biphenyls | CIBA-GEIGY AG (CH) | 1985-04-03 | — | — | EP | disclosed |