SCHEMBL607349

SCHEMBL607349

CS(=O)(=O)c1ccc(C=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.52
PTGS2 P35354 6/20 0.50
CYP2A6 P11509 3/20 0.50
AKR1C3 P42330 1/20 0.48
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46
ALDH1A1 P00352 3/20 0.44
MAOB P27338 1/20 0.44
TYR P14679 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2A13 Q16696 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720714 0.93 MAOB (0.49) ENPP2PTGS2CYP2A6AKR1C3AKR1C2
SCHEMBL4715345 0.93 PTGS2 (0.53) ENPP2PTGS2CYP2A6AKR1C3
Benzaldehyde SCHEMBL28192263 0.91 ALDH1A1 (0.58) PTGS2CYP2A6AKR1C3AKR1C2AKR1C1
SCHEMBL3923767 0.88 ALDH1A1 (0.50) ENPP2PTGS2CYP2A6AKR1C3ALDH1A1
SCHEMBL10649369 0.88 PTGS2 (0.49) ENPP2PTGS2AKR1C3MAOB
SCHEMBL13926394 0.82 CYP2A6 (0.52) CYP2A6ALDH1A1TYRCYP2A13
SCHEMBL9720723 0.82 MAOB (0.55) ENPP2PTGS2AKR1C3AKR1C2AKR1C1
SCHEMBL9720721 0.82 MAOB (0.55) ENPP2PTGS2AKR1C3AKR1C2AKR1C1
SCHEMBL22118701 0.81 CYP2A6 (0.46) ENPP2CYP2A6ALDH1A1TYRCYP2A13
SCHEMBL30673256 0.81 CYP2A6 (0.46) PTGS2CYP2A6ALDH1A1TYRCYP2A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1616 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157695-A Aza-BODIPY photosensitizers with diformyl groups, synthesis and PDT/PTT combined therapy application 北京化工大学 2025-06-17 CN claimed
CN-120058569-A Preparation method of p-methylsulfonyl benzaldehyde 湖北武荆化工新材料有限公司 2025-05-30 CN claimed
CN-119219504-B Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2025-03-14 CN claimed
CN-119591527-A Method for preparing florfenicol intermediate through chiral auxiliary-mediated asymmetric aldol reaction 江苏恒盛药业有限公司 2025-03-11 CN claimed
CN-119570769-A L-threonine aldolase mutant and application thereof in catalytic synthesis of p-methylsulfonyl phenylserine 武汉大学 2025-03-07 CN claimed
CN-119506367-A Method for preparing florfenicol intermediate by double-enzyme system 上海昱菘生物科技有限公司 2025-02-25 CN claimed
US-20250059574-A1 METHODS FOR PREPARING (2S,3R)-P-METHYLSULFONYLPHENYLSERINE TAIZHOU UNIVERSITY (CN) 2025-02-20 US claimed
CN-119219504-A Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2024-12-31 CN claimed
CN-119101091-A DOPO-based phosphorus-nitrogen-sulfur synergistic flame retardant compound and preparation method and application thereof 常州大学 2024-12-10 CN claimed
CN-118497167-B L-threonine transaldolase mutant and application thereof in synthesis of L-p-methylsulfonylbenzylserine 浙江昊清生物科技有限公司 2024-11-22 CN claimed
US-20030216454-A1 Thiazolidine-4-one derivative, method for preparing the same, and pharmaceutical composition containing the same CJ CHEILJEDANG CORPORATION (KR) 2003-11-20 US claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
CN-1389458-A P-methylsulfonyl phenylacrylic acid derivative and preparation method and anti-inflammatory effect thereof UNIV CHINA PHARMACY (CN) 2003-01-08 CN claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
US-4916128-A Thiadiazinones MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-04-10 US claimed
US-4696913-A Novel peptides which are active on the central nervous system and have an action on the cholinergic system HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-29 US claimed
US-4623715-A ANTIDEPRESSANTS HOECHST AKTIENGESELLESCHAFT (DE) 1986-11-18 US claimed
EP-0179332-A2 ZNS-active peptides acting on the cholinergetic system HOECHST AKTIENGESELLSCHAFT (DE) 1986-04-30 EP claimed
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216454-A1 Thiazolidine-4-one derivative, method for preparing the same, and pharmaceutical composition containing the same SLC5A1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NAT1 ENPP2 4884/4885PTGS2 3143/4885CYP2A6 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.