Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.50 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649646 | 0.91 | ALDH1A1 (0.64) | HTTADORA2BSMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL10649965 | 0.89 | LMNA (0.65) | HTTADORA2BSMN1; SMN2RXFP1CASP1 | |
| SCHEMBL10649659 | 0.89 | TSHR (0.65) | HTTADORA2BSMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL10649782 | 0.85 | SMN1; SMN2 (0.55) | HTTADORA2BSMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL10650799 | 0.85 | RXFP1 (0.57) | HTTADORA2BSMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL10653559 | 0.83 | SMN1; SMN2 (0.66) | HTTADORA2BSMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL9317721 | 0.83 | MAPK1 (0.54) | HTTADORA2BSMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL6438430 | 0.82 | ADORA2B (0.56) | HTTADORA2BSMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL10650780 | 0.82 | ADORA2B (0.56) | HTTADORA2BSMN1; SMN2RXFP1LMNA | |
| SCHEMBL10652435 | 0.81 | LMNA (0.58) | HTTADORA2BSMN1; SMN2RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089028-B1 | THEOPHYLLIN DERIVATIVES, AND PROCESS FOR THEIR PREPARATION | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-05-25 | — | — | EP | claimed |