SCHEMBL6438430

SCHEMBL6438430

Cc1nc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)no1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 10/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
RXFP1 Q9HBX9 2/20 0.56
LMNA P02545 3/20 0.55
MAPK1 P28482 1/20 0.55
MAPT P10636 1/20 0.54
HTT P42858 1/20 0.54
ABCC8 Q09428 1/20 0.53
KCNJ11 Q14654 1/20 0.53
KMT2A Q03164 1/20 0.51
ALDH1A1 P00352 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10650189 0.90 ALDH1A1 (0.58) ADORA2BSMN1; SMN2RXFP1LMNAMAPK1
SCHEMBL10649350 0.88 ADORA2B (0.61) ADORA2BSMN1; SMN2RXFP1LMNAMAPK1
SCHEMBL10650780 0.88 ADORA2B (0.56) ADORA2BSMN1; SMN2RXFP1LMNAMAPK1
SCHEMBL10649455 0.87 ADORA2B (0.62) ADORA2BSMN1; SMN2RXFP1LMNAMAPK1
SCHEMBL10651591 0.86 ADORA2B (0.56) ADORA2BSMN1; SMN2RXFP1LMNAMAPK1
SCHEMBL10649548 0.86 ADORA2B (0.60) ADORA2BRXFP1LMNAMAPK1MAPT
SCHEMBL10649699 0.85 ADORA2B (0.54) ADORA2BSMN1; SMN2RXFP1LMNAMAPK1
SCHEMBL10650206 0.85 ADORA2B (0.51) ADORA2BSMN1; SMN2RXFP1LMNAMAPK1
SCHEMBL10651963 0.84 ADORA2B (0.57) ADORA2BSMN1; SMN2RXFP1LMNAMAPK1
SCHEMBL10653621 0.84 ADORA2B (0.57) ADORA2BSMN1; SMN2RXFP1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0089028-B1 THEOPHYLLIN DERIVATIVES, AND PROCESS FOR THEIR PREPARATION CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1988-05-25 EP claimed
US-4565817-A ANTITUSSIVE AGENTS CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1986-01-21 US claimed
EP-0089028-A1 Theophyllin derivatives, and process for their preparation CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1983-09-21 EP claimed
CN-122060909-A Primer for identifying purity of cauliflower hybrid seeds and application thereof 北京市农林科学院 2026-05-19 CN disclosed
US-20250140406-A1 CLASSIFYING TUMORS AND PREDICTING RESPONSIVENESS INSIGHT MOLECULAR DIAGNOSTICS INC. 2025-05-01 US disclosed
WO-2025089727-A1 ELECTRONIC DEVICE AND METHOD FOR PERFORMING ANTIBIOTIC SUSCEPTIBILITY TEST OF MICROORGANISM 주식회사 프로티아 2025-05-01 WO disclosed
CN-114308019-B Alcohol steam activated integral ozone decomposition catalyst and preparation method and application thereof 浙江工业大学 2024-06-14 CN disclosed
CN-117448486-A Application of SSR primer in evaluation of cauliflower resources 北京市农林科学院 2024-01-26 CN disclosed
US-20220244263-A1 METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 US disclosed
CN-114308019-A Alcohol steam activated integral ozone decomposition catalyst and preparation method and application thereof 浙江工业大学 2022-04-12 CN disclosed
US-20050222193-A1 Novel combination for the treatment of airway disorders ALTANA PHARMA AG (DE) 2005-10-06 US disclosed
WO-2005074932-A1 THE USE OF (S) - PANTOPRAZOLE MAGNESIUM FOR THE TREATMENT OF AIRWAY DISORDERS ALTANA PHARMA AG (DE) 2005-08-18 WO disclosed
US-20050165041-A1 Combination for the treatment of airway disorders ALTANA PHARMA AG (DE) 2005-07-28 US disclosed
EP-1517706-A2 COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES ALTANA Pharma AG (DE) 2005-03-30 EP disclosed
WO-2003094968-A2 COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES ALTANA PHARMA AG (DE) 2003-11-20 WO disclosed
EP-0264081-B1 Oxadiazolyl alkyl purin derivatives, their preparation and their use in pharmaceutical compositions CHINOIN GYOGYSZER ES VEGYESZET (HU) 1994-01-05 EP disclosed
EP-0089028-B1 THEOPHYLLIN DERIVATIVES, AND PROCESS FOR THEIR PREPARATION CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1988-05-25 EP disclosed
US-4565817-A ANTITUSSIVE AGENTS CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1986-01-21 US disclosed
EP-0089028-A1 Theophyllin derivatives, and process for their preparation CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1983-09-21 EP disclosed