Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690877 | 0.91 | HTR6 (0.43) | HTR6TACR1FFAR1KDM4EGAA | |
| SCHEMBL10646848 | 0.90 | HTR6 (0.43) | HTR6TACR1FFAR1KDM4EGAA | |
| SCHEMBL10647317 | 0.88 | POLB (0.42) | KDM4EGAANR1I2HTR1ASLC6A2 | |
| SCHEMBL10646450 | 0.86 | FABP4 (0.42) | FFAR1KDM4EGAAMAPTNR1I2 | |
| SCHEMBL10815688 | 0.85 | HTR6 (0.47) | HTR6TACR1FFAR1KDM4ECARM1 | |
| SCHEMBL10647313 | 0.84 | KDM4E (0.41) | KDM4EGAAMAPTNR1I2TSHR | |
| SCHEMBL10914095 | 0.81 | POLB (0.46) | KDM4EGAAMAPTNR1I2HTR1A | |
| SCHEMBL10644589 | 0.81 | KMT2A (0.45) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL10649425 | 0.81 | POLB (0.40) | KDM4EGAANR1I2MEN1KMT2A | |
| SCHEMBL9691722 | 0.80 | KDM4E (0.43) | KDM4EGAAMAPTNR1I2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288758-A2 | Dihydropyridinamides, process for their preparation and their use in medicines | BAYER AG (DE) | 1988-11-02 | — | — | EP | disclosed |