SCHEMBL1065011

SCHEMBL1065011

C=CC(=O)OC(C)[Si](OCC)(OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
TSHR P16473 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HCAR2 Q8TDS4 1/20 0.35
THRB P10828 2/20 0.34
ATM Q13315 1/20 0.34
TGM2 P21980 1/20 0.34
GSTO1 P78417 1/20 0.34
PDE6D O43924 1/20 0.34
ACACB O00763 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
FFAR1 O14842 1/20 0.33
FAAH O00519 1/20 0.33
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1066659 0.88 TSHR (0.37) LMNATSHRALDH1A1HCAR2THRB
SCHEMBL1066663 0.86 ALDH1A1 (0.35) LMNAL3MBTL1TSHRALDH1A1HCAR2
SCHEMBL2476564 0.83 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL1067127 0.79 ALDH1A1 (0.35) LMNATSHRALDH1A1HCAR2THRB
SCHEMBL1066828 0.77 THRB (0.36) LMNATSHRHCAR2THRBGSTO1
SCHEMBL28429178 0.75 ALDH1A1 (0.36) LMNAL3MBTL1TSHRALDH1A1HCAR2
SCHEMBL29277861 0.75 ALDH1A1 (0.36) LMNAL3MBTL1TSHRALDH1A1HCAR2
SCHEMBL1067118 0.74 THRB (0.41) LMNAL3MBTL1TSHRALDH1A1HCAR2
SCHEMBL632703 0.74 SLC1A3 (0.43) LMNAL3MBTL1TSHRALDH1A1HCAR2
SCHEMBL28001576 0.73 TGM2 (0.36) LMNAL3MBTL1TSHRALDH1A1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8829142-B2 Curable composition and process for production of organosilicon compound TOAGOSEI CO., LTD. (JP) 2014-09-09 US disclosed
EP-2270070-B1 CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO LTD (JP) 2014-07-30 EP disclosed
EP-2565217-B1 Curable composition and process for production of organosilicon compound TOAGOSEI CO LTD (JP) 2014-05-14 EP disclosed
US-20130149455-A1 CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO., LTD. (JP) 2013-06-13 US disclosed
EP-2565217-A1 Curable composition and process for production of organosilicon compound TOAGOSEI CO., LTD. (JP) 2013-03-06 EP disclosed
US-20110071255-A1 CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO., LTD. (JP) 2011-03-24 US disclosed
EP-2270070-A1 CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND Toagosei Co., Ltd (JP) 2011-01-05 EP disclosed