Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.52 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416685 | 0.85 | CYP19A1 (0.76) | CYP19A1TBXAS1 | |
| SCHEMBL10656868 | 0.82 | EGLN3 (0.61) | CYP19A1TBXAS1EGLN3 | |
| SCHEMBL15179017 | 0.82 | CYP19A1 (0.64) | CYP19A1TBXAS1 | |
| SCHEMBL11616192 | 0.81 | FOLH1 (0.58) | FOLH1 | |
| SCHEMBL9414537 | 0.78 | CYP19A1 (0.56) | CYP19A1TBXAS1 | |
| SCHEMBL27824075 | 0.77 | CYP19A1 (0.65) | CYP19A1TBXAS1 | |
| SCHEMBL8580210 | 0.76 | TBXAS1 (0.79) | TBXAS1 | |
| SCHEMBL11607374 | 0.75 | ALDH1A1 (0.57) | CYP19A1TBXAS1 | |
| SCHEMBL6992090 | 0.75 | CYP11B1 (0.71) | CYP19A1TBXAS1 | |
| SCHEMBL15173640 | 0.75 | CYP19A1 (0.56) | CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124186-B1 | IMIDAZOLE-ETHANOL ESTERS | GIST-BROCADES N.V. (NL) | 1988-09-21 | — | — | EP | claimed |