Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 2/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.50 |
| ▸ | FNTA | P49354 | 3/20 | 0.42 |
| ▸ | FNTB | P49356 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651486 | 0.73 | PTGS2 (0.43) | GRIA2GRIA4FNTAFNTBKMT2A | |
| SCHEMBL10651230 | 0.73 | GRIA4 (0.51) | GRIA2GRIA4FNTAFNTBKMT2A | |
| SCHEMBL13991798 | 0.68 | ALDH1A1 (0.47) | GRIA2GRIA4FNTAFNTBKMT2A | |
| SCHEMBL1551828 | 0.67 | GRIA2 (0.44) | GRIA2GRIA4KMT2AMAPTL3MBTL1 | |
| SCHEMBL3126306 | 0.67 | GRIA4 (1.00) | GRIA2GRIA4FNTAFNTBKMT2A | |
| SCHEMBL3131405 | 0.65 | GRIA4 (0.79) | GRIA2GRIA4FNTAFNTBMAPT | |
| SCHEMBL21710933 | 0.64 | PTGS2 (0.38) | KMT2AMAPTUSP2KDM4ELMNA | |
| SCHEMBL10653153 | 0.63 | ALOX5 (0.42) | GRIA2GRIA4FNTAFNTBKMT2A | |
| SCHEMBL10653103 | 0.63 | GRIA4 (0.50) | GRIA2GRIA4FNTAFNTBKMT2A | |
| SCHEMBL6050621 | 0.63 | PTGS2 (0.71) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |