Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654899 | 0.80 | KDM4E (0.43) | GRIA2GRIA4KDM4EALDH1A1HTT | |
| SCHEMBL10656112 | 0.78 | ALDH1A1 (0.50) | GRIA2GRIA4KDM4EALDH1A1HTT | |
| SCHEMBL10651545 | 0.74 | HSP90AA1 (0.40) | KDM4EALDH1A1HTTKMT2ALMNA | |
| SCHEMBL10653342 | 0.74 | ATM (0.51) | KDM4EALDH1A1HTTKMT2ALMNA | |
| SCHEMBL10651486 | 0.72 | PTGS2 (0.43) | GRIA2GRIA4KDM4EALDH1A1HTT | |
| SCHEMBL10652386 | 0.72 | GRIA2 (0.42) | GRIA2GRIA4ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10656208 | 0.70 | NPSR1 (0.50) | KDM4EALDH1A1HTTKMT2ALMNA | |
| SCHEMBL10653117 | 0.69 | ABL1 (0.40) | PTGS2 | |
| SCHEMBL10651866 | 0.69 | KDM4E (0.47) | KDM4EALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL15461576 | 0.68 | EPAS1 (0.45) | KDM4EALDH1A1HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |