Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 14/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 14/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 14/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 14/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911224 | 0.86 | ADORA2A (0.41) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL580610 | 0.78 | ADORA2A (0.64) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL4426345 | 0.77 | XDH (0.54) | — | |
| SCHEMBL28413958 | 0.77 | ADORA2A (0.62) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL1065184 | 0.76 | ADORA2A (0.44) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL3474052 | 0.76 | ADORA2A (0.44) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL28410735 | 0.75 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL1831279 | 0.73 | XDH (0.50) | — | |
| SCHEMBL28560268 | 0.71 | ADORA2A (0.51) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL28426470 | 0.71 | CRBN (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652528-A1 | ACTIVATED CARBON INFUSION SOLUTION, PREPARATION METHOD THEREFOR AND USE THEREOF FOR THE MANUFACTURE OF DRUG FOR TREATING CANCER | Chen, Xiaochuan (CN) | 2006-05-03 | — | — | EP | claimed |
| US-20050123613-A1 | Activated carbon infusion solution, preparation method therefor and use thereof for the manufacture of drug for treating cancer | CHEN XIAOCHUAN (CN) | 2005-06-09 | — | — | US | claimed |
| WO-2011130385-A1 | BIOMARKERS FOR HEPATOCELLULAR CANCER | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC | 2011-10-20 | — | — | WO | disclosed |
| EP-1652528-A1 | ACTIVATED CARBON INFUSION SOLUTION, PREPARATION METHOD THEREFOR AND USE THEREOF FOR THE MANUFACTURE OF DRUG FOR TREATING CANCER | Chen, Xiaochuan (CN) | 2006-05-03 | — | — | EP | disclosed |
| US-20050123613-A1 | Activated carbon infusion solution, preparation method therefor and use thereof for the manufacture of drug for treating cancer | CHEN XIAOCHUAN (CN) | 2005-06-09 | — | — | US | disclosed |