Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.53 |
| ▸ | KIF11 | P52732 | 8/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578303 | 0.71 | TDP2 (0.66) | TDP2KIF11 | |
| SCHEMBL31492431 | 0.71 | TDP2 (0.66) | TDP2KIF11 | |
| SCHEMBL74499 | 0.70 | AHR (0.45) | TDP2MEN1KMT2A | |
| SCHEMBL5540047 | 0.69 | PTPN5 (0.44) | TDP2KIF11PTPN5PARP1PARP10 | |
| SCHEMBL18010845 | 0.69 | TDP2 (1.00) | TDP2KIF11PARP1PARP10 | |
| SCHEMBL3224720 | 0.68 | TDP2 (0.66) | TDP2KIF11 | |
| SCHEMBL11707529 | 0.67 | BLM (0.63) | TDP2CYBBNOX3NOX4NOX1 | |
| SCHEMBL30207808 | 0.67 | CYBB (0.53) | PTPN5CYBBNOX3NOX4NOX1 | |
| SCHEMBL2749063 | 0.67 | CYBB (0.53) | PTPN5CYBBNOX3NOX4NOX1 | |
| SCHEMBL6586662 | 0.66 | TDP2 (0.54) | TDP2KIF11PARP1PARP10PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755509-A | Heterocyclic aldose reductase inhibitors and methods of using them | Carbipem (FR) | 1988-07-05 | — | — | US | disclosed |