Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP2 | O95551 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438114 | 1.00 | AHR (0.45) | AHRPDK2ALDH1A1HPGDKDM4E | |
| SCHEMBL9628822 | 0.90 | CYP1A2 (0.50) | AHRPDK2ALDH1A1HPGDKDM4E | |
| SCHEMBL4793929 | 0.75 | ALDH1A1 (0.36) | ALDH1A1HPGDKDM4ECYP1A2MEN1 | |
| SCHEMBL2145401 | 0.75 | KMT2A (0.45) | ALDH1A1HPGDKDM4ECYP1A2MEN1 | |
| SCHEMBL10652401 | 0.70 | TDP2 (0.53) | TDP2MEN1KMT2A | |
| SCHEMBL10435498 | 0.69 | AHR (0.36) | AHRPDK2ALDH1A1HPGDKDM4E | |
| SCHEMBL9449454 | 0.69 | MAPT (0.49) | HPGDTDP2MEN1KMT2AMAPT | |
| SCHEMBL2313287 | 0.67 | AHR (0.70) | AHRPDK2TDP2CASP3CASP7 | |
| SCHEMBL1498003 | 0.67 | ALDH1A1 (0.59) | AHRPDK2ALDH1A1HPGDKDM4E | |
| SCHEMBL10463774 | 0.67 | ALDH1A1 (0.64) | AHRPDK2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 910 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727950-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2026-04-22 | — | — | EP | claimed |
| US-20260048047-A1 | SMALL-MOLECULE ACTIVATORS OF MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE | SCRIPPS RESEARCH INST (US) | 2026-02-19 | — | — | US | claimed |
| EP-4630043-A1 | IMMUNE-ACTIVATING COMPLEXES | Dynamic Cell Therapies, Inc. (US) | 2025-10-15 | — | — | EP | claimed |
| EP-4630446-A1 | ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF | Dynamic Cell Therapies, Inc. (US) | 2025-10-15 | — | — | EP | claimed |
| WO-2025096495-A1 | ARYL FLUOROSULFATE-BASED INHIBITORS AS NOVEL ANTITUBERCULAR AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-05-08 | — | — | WO | claimed |
| US-20250129084-A1 | Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2025-04-24 | — | — | US | claimed |
| EP-4486454-A1 | COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2025-01-08 | — | — | EP | claimed |
| WO-2024256554-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-12-19 | — | — | WO | claimed |
| US-12161655-B2 | Methods of treating mycobacterial infections using tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2024-12-10 | — | — | US | claimed |
| CN-118955428-A | Benzothiazinone vinylidene indene series compound with dibenzothiazepine octacycle system structure and preparation method thereof | 浙大城市学院 | 2024-11-15 | — | — | CN | claimed |
| WO-2001034106-A1 | AGENT FOR COLOURING KERATIN CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-17 | — | — | WO | claimed |
| US-5482921-A | HERBICIDES | SANDOZ LTD. (CH) | 1996-01-09 | — | — | US | claimed |
| EP-0434440-B1 | Benzoxazine derivatives, benzothiazine derivatives and herbicides comprising the same | SUNTORY LTD (JP) | 1995-09-20 | — | — | EP | claimed |
| US-5362706-A | Herbicides especially for mono- or dicotyldoneous plants; pre-and postemergence | SANDOZ LTD. (CH) | 1994-11-08 | — | — | US | claimed |
| EP-0267432-B1 | ANTIBACTERIALLY ACTIVE PYRIDO-BENZOTHIAZINE DERIVATIVES WITH LONG TERM ACTION | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1991-12-27 | — | — | EP | claimed |
| US-4868299-A | Antibacterially active pyrido-benzothiazine derivatives with long-term action | MEDIOLANUM FARMACEUTICI SRL (IT) | 1989-09-19 | — | — | US | claimed |
| US-4833137-A | FUNGICIDES FOR PLANTS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1989-05-23 | — | — | US | claimed |
| EP-0267432-A1 | Antibacterially active pyrido-benzothiazine derivatives with long term action | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1988-05-18 | — | — | EP | claimed |
| EP-0252352-A2 | Highly soluble antibacterially active organic salts of pyridobenzothiazines and their preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1988-01-13 | — | — | EP | claimed |
| EP-0245902-A2 | Benzothiazinone derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-11-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129084-A1 | Compounds | CFTR, TBCA, TBCD | AHR 2218/4885PDK2 1279/4885ALDH1A1 991/4885 |
| US-12161655-B2 | Methods of treating mycobacterial infections using tetracycline compounds | TREH, TBCA, OTC | AHR 4026/4885PDK2 4632/4885ALDH1A1 3284/4885 |
| US-20260048047-A1 | SMALL-MOLECULE ACTIVATORS OF MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE | FNTB, PDE7A, TBL3 | AHR 2393/4885PDK2 2256/4885ALDH1A1 2154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.