Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 4/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27598694 | 0.85 | TDP2 (0.50) | TDP2PARP1PARP10PNMTKIF11 | |
| Ammonia Solution, Strong SCHEMBL28002037 | 0.85 | TDP2 (0.50) | TDP2PARP1PARP10NOTUMPNMT | |
| SCHEMBL27974149 | 0.83 | TDP2 (0.49) | TDP2PARP1PARP10PNMTAADAT | |
| SCHEMBL9491661 | 0.79 | TDP2 (0.50) | TDP2PARP1PARP10NOTUMPNMT | |
| SCHEMBL33527314 | 0.76 | TDP2 (0.59) | TDP2PARP1PARP10PNMTKIF11 | |
| SCHEMBL4893296 | 0.74 | TDP2 (0.57) | TDP2PARP1PARP10CYP1A2CYP2A6 | |
| SCHEMBL6584253 | 0.71 | CYP1A2 (0.50) | TDP2PARP1PARP10CYP1A2NOTUM | |
| SCHEMBL31265568 | 0.71 | TDP2 (0.54) | TDP2PARP1PARP10PNMT | |
| SCHEMBL18010845 | 0.71 | TDP2 (1.00) | TDP2PARP1PARP10KIF11 | |
| SCHEMBL2387705 | 0.70 | PNMT (0.44) | TDP2PARP1PARP10NOTUMPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119595-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| EP-0861837-B1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2004-04-28 | — | — | EP | disclosed |
| US-5968954-A | EXHIBIT SELECTIVE BINDING AFFINITY FOR 5-HYDROXYTRYPTAMINE RECEPTORS | ADIR ET COMPAGNIE (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0861837-A1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-02 | — | — | EP | disclosed |
| US-4217302-A | INSECTICIDES, MITICIDES | ZOECON CORPORATION (US) | 1980-08-12 | — | — | US | disclosed |
| US-4189598-A | INSECTICIDES., MITICIDE | ZOECON CORPORATION (US) | 1980-02-19 | — | — | US | disclosed |