Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.73 |
| ▸ | TP53 | P04637 | 3/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 5/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.68 |
| ▸ | PGR | P06401 | 2/20 | 0.68 |
| ▸ | AR | P10275 | 2/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308659 | 0.90 | LMNA (0.76) | KMT2AMAPTCYP3A4MEN1ALOX15 | |
| SCHEMBL12180360 | 0.90 | LMNA (0.76) | KMT2AMAPTCYP3A4MEN1ALOX15 | |
| SCHEMBL26659960 | 0.90 | LMNA (0.76) | KMT2AMAPTCYP3A4MEN1ALOX15 | |
| SCHEMBL21388230 | 0.89 | CA2 (0.68) | KMT2AMAPTCYP3A4MEN1ALOX15 | |
| SCHEMBL16393393 | 0.89 | CA2 (0.68) | KMT2AMAPTCYP3A4MEN1ALOX15 | |
| SCHEMBL16393337 | 0.89 | CA2 (0.77) | KMT2AMAPTCYP3A4MEN1ALOX15 | |
| SCHEMBL10652542 | 0.88 | LMNA (0.80) | KMT2AMAPTCYP3A4MEN1ALOX15 | |
| SCHEMBL19286796 | 0.87 | MAPT (0.74) | KMT2AMAPTCYP3A4MEN1ALOX15 | |
| SCHEMBL21388241 | 0.86 | MAPT (0.82) | KMT2AMAPTCYP3A4MEN1ALOX15 | |
| Estradiol Propionate SCHEMBL28094685 | 0.86 | MAPT (0.96) | KMT2AMAPTCYP3A4MEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780460-A | Glycoesters of estradiol and estriol | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-10-25 | — | — | US | claimed |
| US-4780460-A | Glycoesters of estradiol and estriol | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-10-25 | — | — | US | disclosed |