SCHEMBL308659

SCHEMBL308659

C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2OC(=O)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 0.76
KMT2A Q03164 7/20 0.76
CYP3A4 P08684 6/20 0.76
MEN1 O00255 5/20 0.76
ALOX15 P16050 3/20 0.76
MAPK1 P28482 3/20 0.76
BRCA1 P38398 1/20 0.76
RECQL P46063 1/20 0.76
MAPT P10636 6/20 0.72
TP53 P04637 4/20 0.72
SMN1; SMN2 Q16637 4/20 0.72
HIF1A Q16665 2/20 0.72
ESR1 P03372 5/20 0.68
ADORA3 P0DMS8 3/20 0.68
PGR P06401 2/20 0.68
AR P10275 2/20 0.68
PTGS1 P23219 2/20 0.68
PDE3A Q14432 2/20 0.68
ATM Q13315 2/20 0.68
POLB P06746 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26659960 1.00 LMNA (0.76) LMNAKMT2ACYP3A4MEN1ALOX15
SCHEMBL12180360 1.00 LMNA (0.76) LMNAKMT2ACYP3A4MEN1ALOX15
SCHEMBL10653348 0.90 KMT2A (0.73) LMNAKMT2ACYP3A4MEN1ALOX15
SCHEMBL3300046 0.90 LMNA (0.80) LMNAKMT2ACYP3A4MEN1ALOX15
SCHEMBL9011258 0.89 LMNA (0.69) LMNAKMT2ACYP3A4MEN1ALOX15
SCHEMBL24103244 0.89 LMNA (0.84) LMNAKMT2ACYP3A4MEN1ALOX15
SCHEMBL3299315 0.88 MAPT (0.81) LMNAKMT2ACYP3A4MEN1ALOX15
SCHEMBL3871356 0.88 CA2 (0.73) LMNAKMT2ACYP3A4MEN1ALOX15
SCHEMBL3866395 0.87 CA2 (0.77) LMNAKMT2ACYP3A4MEN1ALOX15
SCHEMBL147037 0.87 LMNA (1.00) LMNAKMT2ACYP3A4MEN1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 664 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3616756-B1 COMPOSITION FOR PROMOTING HAIR GROWTH, USE OF THE HAIR GROWTH AGENT AND METHOD FOR PRODUCING THE SAME MUELLER KAEHMANN DIETER KLAUS (DE) 2022-03-09 EP claimed
CN-109925538-A A kind of elastic membrane, preparation method and application 易浦润(上海)生物技术有限公司 2019-06-25 CN claimed
CN-109925537-A A kind of elastic membrane, preparation method and application 易浦润(上海)生物技术有限公司 2019-06-25 CN claimed
CN-109925539-A Elastic membrane, preparation method and application thereof 易浦润(上海)生物技术有限公司 2019-06-25 CN claimed
CN-109731206-A A kind of sacculus for biological body vessel bifurcated lesions and application thereof and operation method 中国医学科学院阜外医院 2019-05-10 CN claimed
CN-109609661-A A kind of combination of kidney-yang deficiency exogenous disease mouse model lung tissue qPCR reference gene and its screening technique 山东中医药大学 2019-04-12 CN claimed
CN-109568325-A A kind of endometriosis fibrosis animal model constructing method and its application 上海长海医院 2019-04-05 CN claimed
CN-102813663-B Pharmaceutical composition comprising tetrahydrofolic acid 拜耳知识产权有限责任公司 2019-03-22 CN claimed
CN-109169415-A A kind of production method of all-male snakehead 武汉百瑞生物技术有限公司 2019-01-11 CN claimed
CN-108377939-A A kind of producing method for seed of lucky Hybrid tilapia difficult to understand 广西壮族自治区水产科学研究院 2018-08-10 CN claimed
EP-1087773-A4 VAGINAL ACTIVE AGENT DELIVERY PROCEDURES AND FORMULATIONS THEREOF INTERAG (NZ) 2002-03-13 EP claimed
US-20020028788-A1 Vaginal active agent delivery procedures and formulations thereof INTERAG (NZ) 2002-03-07 US claimed
EP-1087773-A1 VAGINAL ACTIVE AGENT DELIVERY PROCEDURES AND FORMULATIONS THEREOF DEC RESEARCH (NZ) 2001-04-04 EP claimed
WO-2001012101-A1 MULTIPLE MATERIAL DISPENSING INTERAG (NZ) 2001-02-22 WO claimed
EP-0768896-B1 LOW-DOSE STEROID TABLETS CONTAINING GALLIC ACID ESTERS AS ANTIOXIDANT AGENT, PROCESS FOR THE MANUFACTURE OF SAID TABLETS, AND USES OF SAID TABLETS SCHERING AG (DE) 2000-08-16 EP claimed
WO-1999065497-A1 VAGINAL ACTIVE AGENT DELIVERY PROCEDURES AND FORMULATIONS THEREOF DEC RESEARCH (NZ) 1999-12-23 WO claimed
EP-0346014-B1 Therapeutic product for the treatment of peri- or postmenopausal conditions ZENECA LTD (GB) 1994-08-03 EP claimed
US-5183814-A Administering estrogen and antiestrogen IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-02-02 US claimed
EP-0346014-A1 Therapeutic product for the treatment of peri- or postmenopausal conditions ZENECA LIMITED (GB) 1989-12-13 EP claimed
EP-0114003-A1 Antiandrogen and antibiotic treatment of acne and pharmaceutical preparations therefor Mortimer, Christopher Harry, Dr. (GB) 1984-07-25 EP claimed