Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446758 | 0.85 | FDPS (0.41) | FDPSTDP1ALOX5RARBGGPS1 | |
| SCHEMBL1446490 | 0.79 | TDP1 (0.44) | FDPSTDP1ALOX5RARBGGPS1 | |
| SCHEMBL28512770 | 0.79 | ALDH1A1 (0.53) | FDPSTDP1ALOX5RARBGGPS1 | |
| SCHEMBL11806698 | 0.79 | ALDH1A1 (0.53) | FDPSTDP1ALOX5RARBGGPS1 | |
| SCHEMBL4259502 | 0.79 | HRH2 (0.49) | FDPSTDP1ALOX5RARBGGPS1 | |
| SCHEMBL6857008 | 0.78 | TDP1 (0.58) | FDPSTDP1ALOX5RARBGGPS1 | |
| SCHEMBL16340342 | 0.78 | TDP1 (0.58) | FDPSTDP1ALOX5RARBGGPS1 | |
| SCHEMBL27205115 | 0.77 | ALDH1A1 (0.46) | MAPTALDH1A1HPGDKCNH2HRH3 | |
| SCHEMBL10459148 | 0.77 | ALDH1A1 (0.43) | MAPTALDH1A1HPGDKCNH2HRH3 | |
| SCHEMBL4762110 | 0.77 | KCNA3 (0.52) | FDPSTDP1ALOX5RARBGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257048-A1 | OPTICALLY ACTIVE COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-02 | — | — | EP | disclosed |
| WO-1987005018-A2 | OPTICALLY ACTIVE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-08-27 | — | — | WO | disclosed |