Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27706316 | 0.86 | TDP1 (0.41) | HRH2HRH1TDP1ALDH1A1FDPS | |
| SCHEMBL10653441 | 0.79 | FDPS (0.43) | TDP1ALDH1A1FDPSALOX5KMT2A | |
| SCHEMBL13656495 | 0.78 | HRH2 (0.57) | HRH2HRH1TDP1ALDH1A1NPC1 | |
| SCHEMBL1446490 | 0.77 | TDP1 (0.44) | TDP1FDPSALOX5KMT2ARARB | |
| SCHEMBL16340342 | 0.76 | TDP1 (0.58) | TDP1FDPSALOX5SMN1; SMN2KMT2A | |
| SCHEMBL6857008 | 0.76 | TDP1 (0.58) | TDP1FDPSALOX5SMN1; SMN2KMT2A | |
| SCHEMBL4762110 | 0.75 | KCNA3 (0.52) | TDP1FDPSALOX5RARBGGPS1 | |
| SCHEMBL7536898 | 0.75 | KCNA3 (0.52) | TDP1FDPSALOX5RARBGGPS1 | |
| SCHEMBL23875944 | 0.74 | RAB9A (0.44) | HRH2HRH1TDP1ALDH1A1NPC1 | |
| SCHEMBL27540487 | 0.73 | SYK (0.48) | TDP1ALDH1A1ALOX5RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090242876-A1 | CARBAZOLE COMPOUNDS | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2009-10-01 | — | — | US | disclosed |
| US-20080269461-A1 | Polymeric Carbazole Compounds | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2008-10-30 | — | — | US | disclosed |
| EP-1966270-A1 | POLYMERIC CARBAZOLE COMPOUNDS | Koninklijke Philips Electronics N.V. (NL) | 2008-09-10 | — | — | EP | disclosed |
| EP-1838671-B1 | 9,9'- AND 2,2'-SUBSTITUTED 3,3'-BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | KONINKL PHILIPS ELECTRONICS NV (NL) | 2008-06-04 | — | — | EP | disclosed |
| EP-1838671-A2 | 9,9'- AND 2,2'-SUBSTITUTED 3,3'-BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | Koninklijke Philips Electronics N.V. (NL) | 2007-10-03 | — | — | EP | disclosed |
| WO-2007072240-A1 | POLYMERIC CARBAZOLE COMPOUNDS | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006061759-A2 | 9 , 9 ' - AND 2 , 2 ' -SUBSTITUTED 3 , 3 ' -BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090242876-A1 | CARBAZOLE COMPOUNDS | CCNI, IL33, PAICS | HRH2 3147/4885HRH1 3615/4885TDP1 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.