Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 6/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654406 | 0.84 | BRD4 (0.35) | BRD4TP53CREBBPPARP1KMT2A | |
| SCHEMBL28826462 | 0.78 | BRD4 (0.38) | BRD4TP53CREBBPPARP1KMT2A | |
| SCHEMBL4824516 | 0.78 | PARP1 (0.60) | BRD4CREBBPPARP1KMT2APGR | |
| SCHEMBL10358498 | 0.74 | BRD4 (0.55) | BRD4CREBBPPARP1KMT2APGR | |
| SCHEMBL12850583 | 0.74 | TP53 (0.51) | TP53KMT2A | |
| SCHEMBL8904957 | 0.73 | PARP1 (0.40) | BRD4TP53CREBBPPARP1KMT2A | |
| SCHEMBL30991575 | 0.73 | BRD4 (0.55) | BRD4CREBBPPARP1PGRMAOB | |
| SCHEMBL8904960 | 0.73 | PARP1 (0.40) | BRD4TP53CREBBPPARP1KMT2A | |
| SCHEMBL27590550 | 0.72 | MAOB (0.33) | KMT2APGRMAOB | |
| SCHEMBL7466727 | 0.72 | L3MBTL1 (0.53) | BRD4TP53CREBBPKMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290863-A2 | Benzoxazine derivative, process and intermediates for its preparation and its use as herbicide | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-11-17 | — | — | EP | disclosed |