Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476434 | 0.89 | L3MBTL1 (0.63) | L3MBTL1GAATP53CYP3A4TRPV1 | |
| SCHEMBL3598938 | 0.83 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1GAACYP3A4TRPV1 | |
| SCHEMBL7465795 | 0.83 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1GAABRD4MEN1 | |
| SCHEMBL12850583 | 0.82 | TP53 (0.51) | ALDH1A1GAATP53MEN1KMT2A | |
| SCHEMBL7460760 | 0.80 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1GAABRD4MEN1 | |
| SCHEMBL7476036 | 0.80 | ALDH1A1 (0.67) | L3MBTL1ALDH1A1GAACYP3A4BRD4 | |
| SCHEMBL5670577 | 0.79 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1GAATP53MEN1 | |
| SCHEMBL23830643 | 0.78 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1GAACYP3A4TRPV1 | |
| SCHEMBL7468480 | 0.77 | BRD4 (0.42) | L3MBTL1ALDH1A1GAATP53BRD4 | |
| SCHEMBL26121628 | 0.77 | IDO1 (0.44) | ALDH1A1GAATP53BRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |