Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 15/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653826 | 0.69 | CRBN (0.41) | CRBNMMP2 | |
| SCHEMBL10652272 | 0.68 | MEN1 (0.41) | CRBNMMP2 | |
| SCHEMBL10652269 | 0.68 | MEN1 (0.41) | CRBNMMP2 | |
| Hydrochloric Acid SCHEMBL10651039 | 0.67 | MEN1 (0.40) | CRBNMMP2 | |
| SCHEMBL13030159 | 0.66 | CRBN (0.45) | CRBNMMP2 | |
| N4-Hydroxycytosine SCHEMBL24574318 | 0.63 | — | — | |
| N4-Hydroxycytosine SCHEMBL13071713 | 0.63 | — | — | |
| SCHEMBL10656570 | 0.62 | CRBN (0.41) | PTGS2CRBNMMP2 | |
| SCHEMBL10655874 | 0.62 | CRBN (0.41) | PTGS2CRBNMMP2 | |
| SCHEMBL10655308 | 0.61 | MAPT (0.39) | CRBNMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123402-B1 | PYRIMIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |