SCHEMBL890368

SCHEMBL890368

O=C(Cl)c1cccnc1C(=O)Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.55
ALDH1A1 P00352 4/20 0.55
ALOX15 P16050 2/20 0.55
MAPT P10636 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
CYP3A4 P08684 1/20 0.55
TSHR P16473 1/20 0.55
BLM P54132 1/20 0.55
AGER Q15109 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.48
LMNA P02545 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
NAPRT Q6XQN6 2/20 0.44
P2RX7 Q99572 1/20 0.43
CYP1A2 P05177 1/20 0.40
PARP1 P09874 1/20 0.40
GAA P10253 1/20 0.38
DHODH Q02127 2/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28182285 0.98 KDM4E (0.53) KDM4EALDH1A1ALOX15MAPTL3MBTL1
SCHEMBL9198729 0.88 KDM4E (0.74) KDM4EALDH1A1ALOX15MAPTL3MBTL1
SCHEMBL9275469 0.88 KDM4E (0.74) KDM4EALDH1A1ALOX15MAPTL3MBTL1
SCHEMBL10654031 0.86 KDM4E (0.50) KDM4EALDH1A1ALOX15MAPTL3MBTL1
SCHEMBL2372518 0.81 L3MBTL1 (0.57) KDM4EALDH1A1ALOX15MAPTL3MBTL1
SCHEMBL9198739 0.81 L3MBTL1 (0.53) KDM4EALDH1A1ALOX15MAPTL3MBTL1
SCHEMBL3263627 0.80 KDM4E (0.65) KDM4EALDH1A1ALOX15MAPTL3MBTL1
SCHEMBL105459 0.78 SMN1; SMN2 (0.70) KDM4EALDH1A1L3MBTL1SMN1; SMN2LMNA
SCHEMBL1456330 0.78 TLR7 (0.51) KDM4EALDH1A1ALOX15MAPTL3MBTL1
SCHEMBL29799007 0.78 SMN1; SMN2 (0.70) KDM4EALDH1A1L3MBTL1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978373-A Polyarylether sulfone amide and preparation method and application thereof 安徽大学绿色产业创新研究院 2025-05-13 CN claimed
CN-119431424-A Silicon oxime ester-containing photoinitiator, preparation method and application thereof 常州强力先端电子材料有限公司 2025-02-14 CN claimed
CN-114130220-B Preparation method of polytriazine alkali-resistant composite nanofiltration membrane 万华化学集团股份有限公司 2024-06-25 CN claimed
CN-117986232-A Oxime ester photoinitiator, preparation method and application thereof 常州强力电子新材料股份有限公司 2024-05-07 CN claimed
CN-116660424-A Method for detecting quinclorac in honey 秦皇岛海关技术中心 2023-08-29 CN claimed
CN-111518279-B Polysiloxane based on aromatic disulfide bond and application thereof 南京大学 2021-09-28 CN claimed
CN-111518279-A Polysiloxane based on aromatic disulfide bond and application thereof 南京大学 2020-08-11 CN claimed
EP-0198202-B1 NOVEL N-CYCLOHEXYL-POLYCARBOXAMIDE COMPOUND AND DERIVATIVES THEREOF, PROCESSES FOR PREPARING THEM, AND USE OF THEM IN PREPARATION OF HOST-GUEST COMPLEXES MITSUBISHI CORPORATION (JP) 1991-07-17 EP claimed
US-4661254-A AROMATIC POLYAMIDE FROM TRIARYL TRIAMINE AND AROMATIC POLYCARBOXYLIC ACID UOP INC. (US) 1987-04-28 US claimed
EP-0080814-B1 CHROMOGENIC COMPOUNDS YAMAMOTO KAGAKU GOSEI CO., LTD. (JP) 1986-10-15 EP claimed
CN-121892497-A Drug administration method for degrading residual quinolinic acid chloride in tobacco and rice rotation Tian Er 中国烟草总公司福建省公司 2026-04-21 CN disclosed
CN-116640461-B Core-shell dye, near infrared absorbing composition, and film, optical filter and complementary metal oxide semiconductor image sensor using the same 三星SDI株式会社 2025-05-30 CN disclosed
CN-119978373-A Polyarylether sulfone amide and preparation method and application thereof 安徽大学绿色产业创新研究院 2025-05-13 CN disclosed
CN-116135889-B Oxime ester photoinitiator, photo-curing resin composition and application 常州强力电子新材料股份有限公司 2025-04-18 CN disclosed
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2024-10-10 US disclosed
US-4765839-A PAVING THE DOW CHEMICAL COMPANY (US) 1988-08-23 US disclosed
US-4761473-A CORROSION RESISTANCE OF OIL OR GAS WELLS THE DOW CHEMICAL COMPANY (US) 1988-08-02 US disclosed
US-4661254-A AROMATIC POLYAMIDE FROM TRIARYL TRIAMINE AND AROMATIC POLYCARBOXYLIC ACID UOP INC. (US) 1987-04-28 US disclosed
EP-0198202-A2 Novel N-cyclohexyl-polycarboxamide compound and derivatives thereof, processes for preparing them, and use of them in preparation of host-guest complexes MITSUBISHI CORPORATION (JP) 1986-10-22 EP disclosed
EP-0154506-A2 Preparation of organic polymers RAYCHEM LIMITED (GB) 1985-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 KDM4E 3071/4885ALDH1A1 4875/4885ALOX15 313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.