Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.56 |
| ▸ | CBFB | Q13951 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11131070 | 0.83 | LMNA (0.52) | ALDH1A1ALOX15HSD17B10GAAMAPT | |
| SCHEMBL2288991 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ALOX15HSD17B10GAAMAPT | |
| SCHEMBL11341031 | 0.83 | GAA (0.62) | ALDH1A1ALOX15HSD17B10GAAMAPT | |
| SCHEMBL1010313 | 0.81 | ALDH1A1 (0.59) | ALDH1A1ALOX15HSD17B10GAAMAPT | |
| SCHEMBL7644039 | 0.80 | GAA (0.61) | ALDH1A1ALOX15HSD17B10GAAMAPT | |
| SCHEMBL10654430 | 0.78 | RAB9A (0.63) | ALDH1A1ALOX15HSD17B10GAAKDM4E | |
| SCHEMBL11019768 | 0.77 | MAPT (0.53) | ALDH1A1ALOX15HSD17B10GAAMAPT | |
| SCHEMBL11707749 | 0.77 | TP53 (0.44) | ALDH1A1ALOX15HSD17B10GAAMAPT | |
| SCHEMBL7003658 | 0.77 | KDM4E (0.55) | ALDH1A1ALOX15HSD17B10GAAMAPT | |
| SCHEMBL7002965 | 0.77 | MAPT (0.55) | ALDH1A1ALOX15HSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089752-B1 | FLUORAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN RECORDING SYSTEMS | KANZAKI PAPER MANUFACTURING CO., LTD (JP) | 1988-04-20 | — | — | EP | disclosed |
| US-4524373-A | Fluoran derivatives as new compounds, process for preparing the same and recording system utilizing the same as colorless chromogenic material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1985-06-18 | — | — | US | disclosed |
| EP-0089752-A2 | Fluoran derivatives, process for their preparation and their use in recording systems | KANZAKI PAPER MANUFACTURING CO., LTD (JP) | 1983-09-28 | — | — | EP | disclosed |