Aniline

Aniline

SCHEMBL10654772

Nc1ccccc1.O=C(O)Nc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
TP53 P04637 1/20 0.56
EPHX1 P07099 1/20 0.56
EPHX2 P34913 1/20 0.56
CDK9 P50750 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CLK4 Q9HAZ1 1/20 0.56
MAPT P10636 4/20 0.55
RAB9A P51151 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
NAPRT Q6XQN6 1/20 0.52
HSD17B10 Q99714 1/20 0.52
LMNA P02545 2/20 0.51
GAA P10253 1/20 0.50
GFER P55789 1/20 0.50
DDX3X O00571 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL5624205 0.88 TP53 (0.64) TSHRTP53EPHX1EPHX2CDK9
Hydroxyamine SCHEMBL5622599 0.88 EPHX2 (0.64) TSHRTP53EPHX1EPHX2CDK9
SCHEMBL7634 0.88 EPHX2 (0.70) TSHRTP53EPHX1EPHX2CDK9
Benzene SCHEMBL28162617 0.88 EPHX2 (0.70) TSHRTP53EPHX1EPHX2CDK9
Carbamic Acid SCHEMBL4623322 0.86 TP53 (0.61) TSHRTP53EPHX1EPHX2CDK9
SCHEMBL3038302 0.86 MAPT (0.70) TP53EPHX1SMN1; SMN2MAPTRAB9A
SCHEMBL11353365 0.85 EPHX2 (0.67) TSHRTP53EPHX1EPHX2CDK9
Water SCHEMBL9215020 0.85 EPHX2 (0.67) TSHRTP53EPHX1EPHX2CDK9
Iodide SCHEMBL5706290 0.85 EPHX2 (0.67) TSHRTP53EPHX1EPHX2CDK9
Bromide SCHEMBL5706299 0.85 EPHX2 (0.67) TSHRTP53EPHX1EPHX2CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623999-B2 Carbamate production method, carbamate ester production method, and urea derivative production method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2026-05-12 US disclosed
US-12583821-B2 Salt of omecamtiv mecarbil and process for preparing salt CYTOKINETICS, INC. (US) 2026-03-24 US disclosed
EP-2970123-B2 CRYSTALLINE DIHYDROCHLORIDE HYDRATE SALT OF OMECAMTIV MECARBIL AND PROCESS FOR ITS PREPARATION AMGEN INC (US) 2025-12-10 EP disclosed
US-20250243163-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT AMGEN INC. 2025-07-31 US disclosed
US-12221417-B2 Salt of omecamtiv mecarbil and process for preparing salt CYTOKINETICS, INC. (US) 2025-02-11 US disclosed
US-20240317687-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT CYTOKINETICS, INC. 2024-09-26 US disclosed
US-11958809-B2 Salt of omecamtiv mecarbil and process for preparing salt CYTOKINETICS, INC. (US) 2024-04-16 US disclosed
US-20240101517-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT AMGEN INC. 2024-03-28 US disclosed
US-20230212110-A1 CARBAMATE PRODUCTION METHOD, CARBAMATE ESTER PRODUCTION METHOD, AND UREA DERIVATIVE PRODUCTION METHOD NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2023-07-06 US disclosed
EP-4169901-A1 CARBAMATE PRODUCTION METHOD, CARBAMATE ESTER PRODUCTION METHOD, AND UREA DERIVATIVE PRODUCTION METHOD National Institute Of Advanced Industrial Science and Technology (JP) 2023-04-26 EP disclosed
US-11472773-B2 Salt of omecamtiv mecarbil and process for preparing salt CYTOKINETICS, INC. (US) 2022-10-18 US disclosed
US-20220153700-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT CYTOKINETICS, INC. 2022-05-19 US disclosed
EP-0273456-A2 Vapor phase alcoholysis of aminosilanes and carbamatosilanes UNION CARBIDE CORPORATION (US) 1988-07-06 EP disclosed
US-4730074-A Vapor phase alcoholysis of aminosilanes and carbamatosilanes UNION CARBIDE CORPORATION (US) 1988-03-08 US disclosed
EP-0098912-B1 PROCESS FOR THE PREPARATION OF ALKOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-23 EP disclosed
EP-0098911-B1 IMPROVED PROCESS FOR THE PREPARATION OF OXIMATOHYDRIDOSILANES AND AMINOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-16 EP disclosed
EP-0098911-A1 Improved process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
EP-0098912-A1 Process for the preparation of alkoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
US-4395564-A REACTING AN ALCOHOL WITH SILYL-AMINE UNION CARBIDE CORPORATION (US) 1983-07-26 US disclosed
US-4384131-A Process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1983-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243163-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT SI, SLC5A6, SLC28A1 TSHR 4307/4885TP53 2982/4885EPHX1 530/4885
US-20220153700-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT SI, SLC5A6, SLC28A1 TSHR 4307/4885TP53 2982/4885EPHX1 530/4885
US-20240317687-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT SI, SLC5A6, SLC28A1 TSHR 4307/4885TP53 2982/4885EPHX1 530/4885
US-12623999-B2 Carbamate production method, carbamate ester production method, and urea derivative production method CPS1, CA2, CHRM2 TSHR 525/4885TP53 758/4885EPHX1 4810/4885
US-20230212110-A1 CARBAMATE PRODUCTION METHOD, CARBAMATE ESTER PRODUCTION METHOD, AND UREA DERIVATIVE PRODUCTION METHOD CPS1, ATM, OAT TSHR 2160/4885TP53 420/4885EPHX1 4796/4885
US-11472773-B2 Salt of omecamtiv mecarbil and process for preparing salt SI, SLC5A6, SLC28A1 TSHR 4307/4885TP53 2982/4885EPHX1 530/4885
US-20240101517-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT SI, SLC5A6, SLC28A1 TSHR 4307/4885TP53 2982/4885EPHX1 530/4885
US-12583821-B2 Salt of omecamtiv mecarbil and process for preparing salt SLC28A2, SLC28A1, SLC5A11 TSHR 2392/4885TP53 3395/4885EPHX1 3700/4885
US-11958809-B2 Salt of omecamtiv mecarbil and process for preparing salt SI, SLC5A6, SLC28A1 TSHR 4307/4885TP53 2982/4885EPHX1 530/4885
US-12221417-B2 Salt of omecamtiv mecarbil and process for preparing salt SI, SLC5A6, SLC28A1 TSHR 4307/4885TP53 2982/4885EPHX1 530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.