Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652965 | 0.84 | ALDH1A1 (0.38) | PRKCZALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL10654927 | 0.82 | KDM4E (0.40) | PRKCZALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL10654822 | 0.82 | ALDH1A1 (0.39) | PRKCZALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL13991789 | 0.79 | PRKCZ (0.47) | PRKCZALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL15629589 | 0.78 | PRKCZ (0.68) | PRKCZALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL10656103 | 0.75 | ALDH1A1 (0.52) | PRKCZALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL10656208 | 0.73 | NPSR1 (0.50) | PRKCZALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL7574828 | 0.72 | KMT2A (0.55) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL10655997 | 0.72 | ADORA1 (0.42) | PRKCZALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL10658430 | 0.70 | ALDH1A1 (0.39) | ALDH1A1MAPTNPSR1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |