Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654927 | 0.86 | KDM4E (0.40) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL10654822 | 0.86 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDNPSR1ADORA1 | |
| SCHEMBL10656293 | 0.84 | PRKCZ (0.43) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL10655150 | 0.80 | MAPK14 (0.40) | ADORA1ADORA2APRKCZMAPTHTT | |
| SCHEMBL10655997 | 0.76 | ADORA1 (0.42) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL15214875 | 0.76 | PRKCZ (0.60) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL10656806 | 0.73 | NPSR1 (0.42) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL10658430 | 0.73 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL10655996 | 0.71 | ALOX5 (0.39) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL10651774 | 0.68 | ALDH1A1 (0.38) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |