Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 6/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604850 | 0.99 | CTSS (0.49) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL10653891 | 0.88 | CTSS (0.51) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL7064453 | 0.86 | BCHE (0.53) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL10655010 | 0.84 | CTSS (0.64) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL10604848 | 0.83 | CTSS (0.65) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL11010959 | 0.81 | CTSS (0.45) | CTSSCTSKCTSLCTSBACE | |
| Hydrochloric Acid SCHEMBL10607993 | 0.79 | FCER2 (0.47) | — | |
| Hydrochloric Acid SCHEMBL10607238 | 0.79 | FCER2 (0.47) | — | |
| Hydrochloric Acid SCHEMBL10608006 | 0.79 | FCER2 (0.47) | — | |
| SCHEMBL15021100 | 0.79 | CTSS (0.58) | CTSSCTSKCTSLCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4722922-A | RENIN INHIBITION | G. D. SEARLE & CO. (US) | 1988-02-02 | — | — | US | disclosed |
| US-4603121-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1986-07-29 | — | — | US | disclosed |
| US-4495178-A | Enkephalin analogs | G. D. SEARLE & CO. (US) | 1985-01-22 | — | — | US | disclosed |