Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.45 |
| ▸ | CTSK | P43235 | 5/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010955 | 0.85 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL7064453 | 0.83 | BCHE (0.53) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL10604850 | 0.82 | CTSS (0.49) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL10653891 | 0.82 | CTSS (0.51) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL10655014 | 0.81 | CTSS (0.48) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL15021100 | 0.75 | CTSS (0.58) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL13731820 | 0.75 | CTSS (0.58) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL4420857 | 0.72 | ATM (0.55) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL8613335 | 0.71 | CTSK (0.65) | CTSSCTSKMMP1MMP3MMP9 | |
| SCHEMBL2429816 | 0.71 | BCHE (0.49) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136720-A2 | Enkephalin analogs | G.D. Searle & Co. (US) | 1985-04-10 | — | — | EP | disclosed |