Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.51 |
| ▸ | PTPRA | P18433 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653891 | 0.89 | CTSS (0.51) | BCHECTSKCTSSCTSBCTSL | |
| SCHEMBL10604850 | 0.87 | CTSS (0.49) | BCHECTSKCTSSCTSBCTSL | |
| SCHEMBL10655014 | 0.86 | CTSS (0.48) | BCHECTSKCTSSCTSBCTSL | |
| SCHEMBL11010959 | 0.83 | CTSS (0.45) | BCHECTSKCTSSCTSBCTSL | |
| SCHEMBL7064457 | 0.82 | CTSK (0.69) | CTSKCTSSCTSBCTSLPTPN1 | |
| SCHEMBL8613335 | 0.82 | CTSK (0.65) | CTSKCTSS | |
| SCHEMBL15021100 | 0.82 | CTSS (0.58) | CTSKCTSSCTSBCTSLAKT1 | |
| SCHEMBL13731820 | 0.82 | CTSS (0.58) | CTSKCTSSCTSBCTSLAKT1 | |
| SCHEMBL3174229 | 0.81 | PTPN1 (0.68) | CTSKCTSSCTSBCTSLPTPN1 | |
| SCHEMBL31628751 | 0.81 | PTPN1 (0.68) | CTSKCTSSCTSBCTSLPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313696-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018323-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |