Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Creatine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 18/20 | 0.38 |
| ▸ | CA2 | P00918 | 16/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Creatine SCHEMBL9568829 | 0.96 | NOS3 (0.39) | NOS3NOS1NOS2CA1CA2 | |
| Creatine SCHEMBL939498 | 0.94 | CA1 (0.37) | NOS3NOS1NOS2CA1CA2 | |
| Creatine SCHEMBL3816605 | 0.92 | CA1 (0.41) | NOS3NOS1NOS2CA1CA2 | |
| Creatine SCHEMBL4269044 | 0.92 | CA1 (0.41) | NOS3NOS1NOS2CA1CA2 | |
| Creatine SCHEMBL7858043 | 0.88 | CA1 (0.41) | NOS3NOS1NOS2CA1CA2 | |
| Creatine SCHEMBL5569335 | 0.88 | CA1 (0.41) | NOS3NOS1NOS2CA1CA2 | |
| Creatine SCHEMBL6673726 | 0.88 | CA1 (0.41) | NOS3NOS1NOS2CA1CA2 | |
| Creatine SCHEMBL4885845 | 0.88 | CA1 (0.41) | NOS3NOS1NOS2CA1CA2 | |
| Creatine SCHEMBL3807770 | 0.88 | CA1 (0.41) | NOS3NOS1NOS2CA1CA2 | |
| Creatine SCHEMBL675800 | 0.88 | CA1 (0.41) | NOS3NOS1NOS2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122012183-A | Water-based cleaning agent and preparation method and application thereof | 广东波达机电设备有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-120025566-A | Multifunctional radix puerariae powder hydrogel flexible conductive sensor and preparation method and application thereof | 湖南省林业科学院 | 2025-05-23 | — | — | CN | claimed |
| CN-116172950-B | Creatine phosphate sodium injection for myocardial protection | 河南省人民医院 | 2025-02-07 | — | — | CN | claimed |
| US-20240376164-A1 | COMPOSITIONS AND METHODS FOR TREATING LEBER'S HEREDITARY OPTIC NEUROPATHY CAUSED BY ND4 MUTATION | Wuhan Neurophth Biotechnology Limited Company (CN) | 2024-11-14 | — | — | US | claimed |
| EP-4382601-A1 | COMPOSITION AND METHOD FOR TREATING LEBER'S HEREDITARY OPTIC NEUROPATHY CAUSED BY ND4 MUTATION | Wuhan Neurophth Biotechnology Limited Company (CN) | 2024-06-12 | — | — | EP | claimed |
| CN-112816609-B | Method for detecting creatine phosphate sodium residue in preparation production process | 重庆圣华曦药业股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117143969-A | Application of modified molecular enzyme in molecular immunochromatography detection | 深度进化(广州)生物技术有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-116570730-A | Nanometer medicine carrying granule for resisting mononuclear macrophage phagocytosis and preparation method and application thereof | 哈尔滨医科大学 | 2023-08-11 | — | — | CN | claimed |
| CN-114983948-B | Pharmaceutical composition containing creatine phosphate sodium and preparation method thereof | 郑州市中心医院 | 2023-06-23 | — | — | CN | claimed |
| CN-111777636-B | Preparation method of medicine for myocardial protection | 山东罗欣药业集团股份有限公司 | 2023-06-16 | — | — | CN | claimed |
| CN-101313910-B | Preparation technique for sodium phosphocreatine freeze-dried injection | SHANGHAI CRMED SCIENCE CO LTD | 2010-11-03 | — | — | CN | claimed |
| CN-101812088-A | High-purity creatine phosphate sodium compound | HAINAN MEIDA PHARMACEUTICAL CO | 2010-08-25 | — | — | CN | claimed |
| CN-101474159-B | Creatine phosphate sodium microballoon lyophilized preparation and method for producing the same | HAINAN MEIDA PHARMACEUTICAL CO | 2010-06-23 | — | — | CN | claimed |
| CN-101732263-A | Creatine phosphate sodium freeze-dried preparation and method for preparing same | YANG JUN | 2010-06-16 | — | — | CN | claimed |
| CN-101716160-A | Creatine phosphate sodium oral solid preparation and preparation method thereof | HARBIN BOLAI PHARMACEUTICAL CO | 2010-06-02 | — | — | CN | claimed |
| CN-101530391-A | Creatine phosphate sodium lipidosome freeze-dried preparation and preparation method thereof | MING WANG | 2009-09-16 | — | — | CN | claimed |
| CN-101486730-A | Creatine phosphate sodium compound and method for synthesizing the same | XIANFENG ZHENG (CN) | 2009-07-22 | — | — | CN | claimed |
| CN-101474159-A | Creatine phosphate sodium microballoon lyophilized preparation and method for producing the same | HAINAN MEIDA PHARMACEUTICAL CO (CN) | 2009-07-08 | — | — | CN | claimed |
| CN-101313910-A | Preparation technique for sodium phosphocreatine freeze-dried injection | SHANGHAI CRMED SCIENCE CO LTD (CN) | 2008-12-03 | — | — | CN | claimed |
| US-5665802-A | REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-09-09 | — | — | US | claimed |