Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Creatine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 19/20 | 0.37 |
| ▸ | CA2 | P00918 | 17/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Creatine SCHEMBL1065566 | 0.94 | NOS3 (0.39) | CA1CA2NOS3NOS1NOS2 | |
| Creatine SCHEMBL9568829 | 0.91 | NOS3 (0.39) | CA1CA2NOS3NOS1NOS2 | |
| Creatine SCHEMBL4269044 | 0.90 | CA1 (0.41) | CA1CA2NOS3NOS1NOS2 | |
| Creatine SCHEMBL3816605 | 0.90 | CA1 (0.41) | CA1CA2NOS3NOS1NOS2 | |
| Creatine SCHEMBL4885845 | 0.86 | CA1 (0.41) | CA1CA2NOS3NOS1NOS2 | |
| Creatine SCHEMBL675800 | 0.86 | CA1 (0.41) | CA1CA2NOS3NOS1NOS2 | |
| Creatine SCHEMBL3807770 | 0.86 | CA1 (0.41) | CA1CA2NOS3NOS1NOS2 | |
| Creatine SCHEMBL7858043 | 0.86 | CA1 (0.41) | CA1CA2NOS3NOS1NOS2 | |
| Creatine SCHEMBL6673726 | 0.86 | CA1 (0.41) | CA1CA2NOS3NOS1NOS2 | |
| Creatine SCHEMBL5569335 | 0.86 | CA1 (0.41) | CA1CA2NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4534691-A1 | METHOD FOR MAINTAINING NANOPORE SEQUENCING SPEED | BGI Shenzhen (CN) | 2025-04-09 | — | — | EP | claimed |
| US-20250092452-A1 | METHOD FOR MAINTAINING NANOPORE SEQUENCING SPEED | BGI SHENZHEN (CN) | 2025-03-20 | — | — | US | claimed |
| CN-118086581-A | Primer, probe, reagent and method for rapidly detecting PRV (pseudorabies virus) | 甘肃康承利新生物科技开发有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117363764-A | Primer group for detecting helicobacter pylori through isothermal amplification and microfluidic chip | 上海北昂医药科技股份有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-117144028-A | Primer, probe and detection kit for detecting mycobacterium tuberculosis complex | 上海北昂医药科技股份有限公司 | 2023-12-01 | — | — | CN | claimed |
| WO-2023225988-A1 | METHOD FOR MAINTAINING NANOPORE SEQUENCING SPEED | 深圳华大生命科学研究院 | 2023-11-30 | — | — | WO | claimed |
| CN-116790820-A | Primer, probe, reagent and method for rapidly detecting bovine viral diarrhea BVDV virus at normal temperature and isothermal condition | 甘肃康承利新生物科技开发有限公司 | 2023-09-22 | — | — | CN | claimed |
| CN-116672510-A | Multi-dimensional bionic full-degradable metal-hydrogel composite bone repair material and preparation method thereof | 北京大学深圳医院 | 2023-09-01 | — | — | CN | claimed |
| CN-116064776-A | Primer-probe composition and kit for constant temperature rapid detection of human Y chromosome microdeletion | 上海北昂医药科技股份有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-115976197-A | Kit and method for rapidly detecting gout ABCG2SNP genotype based on CRISPR-Cas13 | 湖南握新生物科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-112063735-A | Primer and probe for detecting polymyxin drug-resistant gene mcr-5 and application | 山东省兽药质量检验所(山东省畜产品质量检测中心) | 2020-12-11 | — | — | CN | claimed |
| CN-112011631-A | RPA detection primer group, kit and method for drug-resistant gene sul2 | 山东省兽药质量检验所(山东省畜产品质量检测中心) | 2020-12-01 | — | — | CN | claimed |
| CN-112011632-A | RPA detection primer group, kit and method for polymyxin drug-resistant gene mcr-4 | 山东省兽药质量检验所(山东省畜产品质量检测中心) | 2020-12-01 | — | — | CN | claimed |
| CN-111996272-A | RPA detection primer group, kit and method for drug-resistant gene mcr-8 | 山东省兽药质量检验所(山东省畜产品质量检测中心) | 2020-11-27 | — | — | CN | claimed |
| CN-111733284-A | Primer, probe, reagent and method for quickly detecting feline parvovirus at normal temperature and isothermal temperature | 潍坊安普未来生物科技有限公司 | 2020-10-02 | — | — | CN | claimed |
| CN-111690776-A | Primer, probe, reagent, method and kit for quickly detecting novel coronavirus SARS-CoV-2 at normal temperature and isothermal | 潍坊安普未来生物科技有限公司 | 2020-09-22 | — | — | CN | claimed |
| CN-111621579-A | Primer, probe, reagent and method for quickly detecting vibrio parahaemolyticus at normal temperature and isothermal temperature | 潍坊安普未来生物科技有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-111187857-A | Primer pair, kit and preparation method and application of kit for detecting novel coronavirus through isothermal amplification | 深圳市芯思微生物科技有限公司 | 2020-05-22 | — | — | CN | claimed |
| CN-111037156-A | Preparation method of regulating particles for sintered flux | 胡隆燕 | 2020-04-21 | — | — | CN | claimed |
| CN-103172661-A | Preparation method of phosphocreatine disodium salt | Chongqing yaoyou pharmaceutical co ltd | 2013-06-26 | — | — | CN | claimed |