Creatine

Creatine

SCHEMBL939498

CN(CC(=O)[O-])C(=N)N.O=P([O-])(O)O.[Na+].[Na+]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Creatine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 19/20 0.37
▸ CA2 P00918 17/20 0.37
▸ NOS3 P29474 1/20 0.34
▸ NOS1 P29475 1/20 0.34
▸ NOS2 P35228 1/20 0.34
▸ CA4 P22748 2/20 0.30
▸ CA5A P35218 2/20 0.30
▸ CA5B Q9Y2D0 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Creatine SCHEMBL1065566 0.94 NOS3 (0.39) CA1CA2NOS3NOS1NOS2
Creatine SCHEMBL9568829 0.91 NOS3 (0.39) CA1CA2NOS3NOS1NOS2
Creatine SCHEMBL4269044 0.90 CA1 (0.41) CA1CA2NOS3NOS1NOS2
Creatine SCHEMBL3816605 0.90 CA1 (0.41) CA1CA2NOS3NOS1NOS2
Creatine SCHEMBL4885845 0.86 CA1 (0.41) CA1CA2NOS3NOS1NOS2
Creatine SCHEMBL675800 0.86 CA1 (0.41) CA1CA2NOS3NOS1NOS2
Creatine SCHEMBL3807770 0.86 CA1 (0.41) CA1CA2NOS3NOS1NOS2
Creatine SCHEMBL7858043 0.86 CA1 (0.41) CA1CA2NOS3NOS1NOS2
Creatine SCHEMBL6673726 0.86 CA1 (0.41) CA1CA2NOS3NOS1NOS2
Creatine SCHEMBL5569335 0.86 CA1 (0.41) CA1CA2NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4534691-A1 METHOD FOR MAINTAINING NANOPORE SEQUENCING SPEED BGI Shenzhen (CN) 2025-04-09 — — EP claimed
US-20250092452-A1 METHOD FOR MAINTAINING NANOPORE SEQUENCING SPEED BGI SHENZHEN (CN) 2025-03-20 — — US claimed
CN-118086581-A Primer, probe, reagent and method for rapidly detecting PRV (pseudorabies virus) 甘肃康承利新生物科技开发有限公司 2024-05-28 — — CN claimed
CN-117363764-A Primer group for detecting helicobacter pylori through isothermal amplification and microfluidic chip 上海北昂医药科技股份有限公司 2024-01-09 — — CN claimed
CN-117144028-A Primer, probe and detection kit for detecting mycobacterium tuberculosis complex 上海北昂医药科技股份有限公司 2023-12-01 — — CN claimed
WO-2023225988-A1 METHOD FOR MAINTAINING NANOPORE SEQUENCING SPEED 深圳华大生命科学研究院 2023-11-30 — — WO claimed
CN-116790820-A Primer, probe, reagent and method for rapidly detecting bovine viral diarrhea BVDV virus at normal temperature and isothermal condition 甘肃康承利新生物科技开发有限公司 2023-09-22 — — CN claimed
CN-116672510-A Multi-dimensional bionic full-degradable metal-hydrogel composite bone repair material and preparation method thereof 北京大学深圳医院 2023-09-01 — — CN claimed
CN-116064776-A Primer-probe composition and kit for constant temperature rapid detection of human Y chromosome microdeletion 上海北昂医药科技股份有限公司 2023-05-05 — — CN claimed
CN-115976197-A Kit and method for rapidly detecting gout ABCG2SNP genotype based on CRISPR-Cas13 湖南握新生物科技有限公司 2023-04-18 — — CN claimed
CN-112063735-A Primer and probe for detecting polymyxin drug-resistant gene mcr-5 and application 山东省兽药质量检验所(山东省畜产品质量检测中心) 2020-12-11 — — CN claimed
CN-112011631-A RPA detection primer group, kit and method for drug-resistant gene sul2 山东省兽药质量检验所(山东省畜产品质量检测中心) 2020-12-01 — — CN claimed
CN-112011632-A RPA detection primer group, kit and method for polymyxin drug-resistant gene mcr-4 山东省兽药质量检验所(山东省畜产品质量检测中心) 2020-12-01 — — CN claimed
CN-111996272-A RPA detection primer group, kit and method for drug-resistant gene mcr-8 山东省兽药质量检验所(山东省畜产品质量检测中心) 2020-11-27 — — CN claimed
CN-111733284-A Primer, probe, reagent and method for quickly detecting feline parvovirus at normal temperature and isothermal temperature 潍坊安普未来生物科技有限公司 2020-10-02 — — CN claimed
CN-111690776-A Primer, probe, reagent, method and kit for quickly detecting novel coronavirus SARS-CoV-2 at normal temperature and isothermal 潍坊安普未来生物科技有限公司 2020-09-22 — — CN claimed
CN-111621579-A Primer, probe, reagent and method for quickly detecting vibrio parahaemolyticus at normal temperature and isothermal temperature 潍坊安普未来生物科技有限公司 2020-09-04 — — CN claimed
CN-111187857-A Primer pair, kit and preparation method and application of kit for detecting novel coronavirus through isothermal amplification 深圳市芯思微生物科技有限公司 2020-05-22 — — CN claimed
CN-111037156-A Preparation method of regulating particles for sintered flux 胡隆燕 2020-04-21 — — CN claimed
CN-103172661-A Preparation method of phosphocreatine disodium salt Chongqing yaoyou pharmaceutical co ltd 2013-06-26 — — CN claimed
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