Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130270 | 0.87 | USP2 (0.46) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL25236221 | 0.80 | USP2 (0.40) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL30731572 | 0.80 | — | — | |
| SCHEMBL27379355 | 0.78 | — | — | |
| SCHEMBL15262439 | 0.78 | USP2 (0.39) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL17017227 | 0.77 | USP2 (0.42) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL2058171 | 0.77 | USP2 (0.42) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL26548775 | 0.77 | USP2 (0.42) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL2057201 | 0.76 | USP2 (0.46) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL822934 | 0.76 | USP2 (0.46) | USP2TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117352837-A | Electrolyte for lithium secondary battery and lithium secondary battery comprising same | SK新能源株式会社 | 2024-01-05 | — | — | CN | disclosed |
| US-9994558-B2 | Multicyclic compounds and methods of using same | Karyopharm Therapeutics Inc. (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170096417-A1 | Multicyclic Compounds And Methods Of Using Same | Karyopharm Therapeutics Inc. (US) | 2017-04-06 | — | — | US | disclosed |
| US-9533945-B2 | Ketene imine compound, polyester film, back sheet for solar cell module and solar cell module | FUJIFILM CORPORATION (JP) | 2017-01-03 | — | — | US | disclosed |
| US-9365499-B2 | 9-aminomethyl substituted tetracycline compounds | KBP BIOSCIENCES CO., LTD. (CN) | 2016-06-14 | — | — | US | disclosed |
| US-9346822-B2 | Thienopyrimidine compounds and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-05-24 | — | — | US | disclosed |
| US-20150232419-A1 | KETENE IMINE COMPOUND, POLYESTER FILM, BACK SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE | FUJIFILM CORPORATION (JP) | 2015-08-20 | — | — | US | disclosed |
| US-20140221381-A1 | THIENOPYRIMIDINE COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20140179638-A1 | 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS | KBP BIOSCIENCES CO., LTD. (CN) | 2014-06-26 | — | — | US | disclosed |
| US-8735401-B2 | Thienopyrimidine compounds and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-05-27 | — | — | US | disclosed |
| US-8637557-B2 | Aminothiazole derivative | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2014-01-28 | — | — | US | disclosed |
| US-20120220767-A1 | AMINOTHIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-08-30 | — | — | US | disclosed |
| US-20120071486-A1 | THIENOPYRIMIDINE COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
| WO-2011048936-A1 | AMINOTHIAZOLE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220767-A1 | AMINOTHIAZOLE DERIVATIVE | AKT3, AKT2, JAK1 | USP2 4254/4885TSHR 1612/4885KDM4E 3690/4885 |
| US-20120071486-A1 | THIENOPYRIMIDINE COMPOUNDS AND USE THEREOF | GNRHR, KISS1R, NR5A1 | USP2 4602/4885TSHR 15/4885KDM4E 814/4885 |
| US-20170096417-A1 | Multicyclic Compounds And Methods Of Using Same | PAK4, PAK5, PAK1 | USP2 4486/4885TSHR 4639/4885KDM4E 611/4885 |
| US-20150232419-A1 | KETENE IMINE COMPOUND, POLYESTER FILM, BACK SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE | KRT18, PRRC2C, PKN1 | USP2 3233/4885TSHR 3728/4885KDM4E 142/4885 |
| US-20140221381-A1 | THIENOPYRIMIDINE COMPOUNDS AND USE THEREOF | GNRHR, KISS1R, NR5A1 | USP2 4602/4885TSHR 15/4885KDM4E 814/4885 |
| US-20140179638-A1 | 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS | TET3, TET1, PRMT9 | USP2 4164/4885TSHR 912/4885KDM4E 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.