SCHEMBL822934

SCHEMBL822934

CC(C)(C)COS(C)(=O)=O

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.46
TSHR P16473 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MMP9 P14780 1/20 0.46
ALOX15 P16050 1/20 0.46
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9130270 0.82 USP2 (0.46) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL2057201 0.82 USP2 (0.46) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL1742189 0.79 ALDH1A1 (0.48) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL2103021 0.79 CYP2C19 (0.39) CYP2C19
SCHEMBL23674320 0.78 USP2 (0.42) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL21025314 0.78 USP2 (0.42) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL12999204 0.78 USP2 (0.42) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL5717997 0.78 CYP2C19 (0.35) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL15262716 0.78 USP2 (0.42) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL1965705 0.78 USP2 (0.42) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240279160-A1 METHOD FOR SYNTHESIZING 9-AMINOMETHYL TETRACYCLINE COMPOUNDS HOVIONE SCIENTIA LIMITED (IE) 2024-08-22 US disclosed
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS FIREFLY BIO, INC. 2024-02-29 US disclosed
EP-3953360-B1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) HOFFMANN LA ROCHE (CH) 2024-02-28 EP disclosed
CN-117616008-A Synthesis method of 9-aminomethyl tetracycline compound 好利安科技有限公司 2024-02-27 CN disclosed
CN-117279895-A (hetero) arylamide compound and pest control agent 日本曹达株式会社 2023-12-22 CN disclosed
US-20230277570-A1 ENPP1 Inhibitors and Their Use for the Treatment of Cancer THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-09-07 US disclosed
CN-113453554-B herbicidal composition 先正达农作物保护股份公司 2023-09-05 CN disclosed
CN-111032640-B Herbicidal compounds 先正达参股股份有限公司 2023-08-08 CN disclosed
EP-3923724-B1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-07-26 EP disclosed
US-11618743-B2 Herbicidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2023-04-04 US disclosed
US-7365091-B2 Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of PHEX ENOBIA PHARMA (CA) 2008-04-29 US disclosed
US-20080064718-A1 INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY METHYLGENE INC. (CA) 2008-03-13 US disclosed
US-20070293530-A1 SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS METHYLGENE INC. (CA) 2007-12-20 US disclosed
US-20070249697-A1 Novel Imidazolidine Derivatives CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-10-25 US disclosed
US-20070249697-A1 Novel Imidazolidine Derivatives CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-10-25 US disclosed
US-7271188-B2 Imidazolidine derivatives CHUGAI SEIKAYU KABUSHIKI KAISHA (JP) 2007-09-18 US disclosed
US-7271188-B2 Imidazolidine derivatives CHUGAI SEIKAYU KABUSHIKI KAISHA (JP) 2007-09-18 US disclosed
US-20070015026-A1 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. 2007-01-18 US disclosed
US-20070015026-A1 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. 2007-01-18 US disclosed
US-6204386-B1 PYRIDINIUM COMPOUND ARTEVA NORTH AMERICA S.A.R.L. (CH) 2001-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11618743-B2 Herbicidal compounds DDT, ACHE, GSTO1 USP2 2000/4885TSHR 1475/4885KDM4E 1194/4885
US-20080064718-A1 INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY HGF, ERBB2, MET USP2 2806/4885TSHR 1253/4885KDM4E 2282/4885
US-20240279160-A1 METHOD FOR SYNTHESIZING 9-AMINOMETHYL TETRACYCLINE COMPOUNDS TET1, TET3, TET2 USP2 1854/4885TSHR 1415/4885KDM4E 299/4885
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS TPX2, H1-4, MAPT USP2 3595/4885TSHR 1144/4885KDM4E 743/4885
US-20070293530-A1 SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS HDAC1, HDAC11, HAT1 USP2 1411/4885TSHR 1262/4885KDM4E 215/4885
US-20070249697-A1 Novel Imidazolidine Derivatives CYP3A4, CYP4B1, OPRD1 USP2 3695/4885TSHR 1646/4885KDM4E 1337/4885
US-20230277570-A1 ENPP1 Inhibitors and Their Use for the Treatment of Cancer ENPP1, ENPP3, ENTPD1 USP2 855/4885TSHR 3941/4885KDM4E 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.