SCHEMBL9130270

SCHEMBL9130270

CC(C)(COS(C)(=O)=O)COS(C)(=O)=O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.46
TSHR P16473 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MMP9 P14780 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15262439 0.90 USP2 (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL10656 0.87 USP2 (0.40) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL2057201 0.82 USP2 (0.46) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL822934 0.82 USP2 (0.46) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL4429699 0.81 CA1 (0.37) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL12014987 0.81 ALDH1A1 (0.36) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL14681679 0.81 KDM4E (0.36) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL17466427 0.81 KDM4E (0.32) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL253966 0.81 KDM4E (0.32) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL16592979 0.79 TSHR (0.40) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2738156-B1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS KBP BIOSCIENCES USA INC (US) 2018-01-03 EP disclosed
US-9365499-B2 9-aminomethyl substituted tetracycline compounds KBP BIOSCIENCES CO., LTD. (CN) 2016-06-14 US disclosed
US-9365499-B2 9-aminomethyl substituted tetracycline compounds KBP BIOSCIENCES CO., LTD. (CN) 2016-06-14 US disclosed
EP-1751169-B1 BRIDGED BI-AROMATIC CATALYSTS, COMPLEXES, AND METHOD OF USING THE SAME SYMYX SOLUTIONS INC (US) 2016-04-13 EP disclosed
US-9240614-B2 Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES, LTD. (JP) 2016-01-19 US disclosed
US-20150232419-A1 KETENE IMINE COMPOUND, POLYESTER FILM, BACK SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE FUJIFILM CORPORATION (JP) 2015-08-20 US disclosed
EP-2579377-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES (JP) 2014-09-03 EP disclosed
US-20140179638-A1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS KBP BIOSCIENCES CO., LTD. (CN) 2014-06-26 US disclosed
US-20140179638-A1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS KBP BIOSCIENCES CO., LTD. (CN) 2014-06-26 US disclosed
EP-2738156-A1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUND KBP Biosciences Co., Ltd. (CN) 2014-06-04 EP disclosed
EP-2738156-A1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUND KBP Biosciences Co., Ltd. (CN) 2014-06-04 EP disclosed
EP-2579377-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2013-04-10 EP disclosed
US-20130071733-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2013-03-21 US disclosed
WO-2013018524-A1 PHOTOSENSITIVE RESIN COMPOSITION, MATERIAL FOR FORMING RELIEF PATTERN, PHOTOSENSITIVE FILM, POLYIMIDE FILM, CURED RELIEF PATTERN AND METHOD FOR PRODUCING SAME, AND SEMICONDUCTOR DEVICE 富士フイルム株式会社 (JP) 2013-02-07 WO disclosed
WO-2013013505-A1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUND 山东亨利医药科技有限责任公司 (CN) 2013-01-31 WO disclosed
US-7241714-B2 Bridged bi-aromatic catalysts, complexes, and methods of using the same SYMYX TECHNOLOGIES, INC. (US) 2007-07-10 US disclosed
US-7241714-B2 Bridged bi-aromatic catalysts, complexes, and methods of using the same SYMYX TECHNOLOGIES, INC. (US) 2007-07-10 US disclosed
US-5416065-A Herbicidal thiadiazabicyclooctanes CIBA-GEIGY CORPORATION (US) 1995-05-16 US disclosed
EP-0600833-A1 Herbicidal thiediazabicyclo-octanes CIBA-GEIGY AG (CH) 1994-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150232419-A1 KETENE IMINE COMPOUND, POLYESTER FILM, BACK SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE KRT18, PRRC2C, PKN1 USP2 3233/4885TSHR 3728/4885KDM4E 142/4885
US-20140179638-A1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS TET3, TET1, PRMT9 USP2 4164/4885TSHR 912/4885KDM4E 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.