Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015645 | 0.90 | OPRM1 (0.41) | CASP1CASP7OPRM1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10656009 | 0.89 | OPRM1 (0.40) | CASP1CASP7OPRM1MEN1KMT2A | |
| SCHEMBL10653491 | 0.89 | OPRM1 (0.42) | CASP1CASP7OPRM1MEN1KMT2A | |
| SCHEMBL11015572 | 0.88 | OPRM1 (0.43) | CASP1CASP7OPRM1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10655291 | 0.88 | OPRM1 (0.41) | CASP1CASP7OPRM1MEN1KMT2A | |
| SCHEMBL10653284 | 0.86 | TRPV1 (0.37) | CASP1CASP7OPRM1MEN1KMT2A | |
| SCHEMBL10656530 | 0.86 | KMT2A (0.39) | CASP1CASP7OPRM1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10652939 | 0.86 | OPRM1 (0.42) | CASP1CASP7OPRM1MEN1KMT2A | |
| SCHEMBL11014353 | 0.86 | KMT2A (0.37) | CASP1CASP7OPRM1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10651518 | 0.85 | KMT2A (0.38) | CASP1CASP7OPRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141968-B1 | PYRROLYLAMINOPIPERIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-05-18 | — | — | EP | claimed |